Computed tomography and magnetic resonance imaging approaches to Graves' ophthalmopathy: a narrative review.

Front Endocrinol (Lausanne)

Department of Anesthesiology, Oncology and Radiology, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil.

Published: January 2024

AI Article Synopsis

  • Graves' ophthalmopathy (GO) affects many patients with Graves' disease and can lead to issues ranging from mild irritation to vision loss.
  • Diagnosis typically relies on clinical findings and lab tests, with orbital imaging techniques like MRI and CT being crucial for assessing the condition and planning treatment.
  • A review of 92 studies from 1979 to 2020 highlights various diagnostic methods for GO, but emphasizes the need for further validation and standardization in measuring and reporting outcomes in thyroid eye disease.

Article Abstract

Graves' ophthalmopathy (GO) affects up to 50% of patients with Graves' disease (GD) ranging from mild ocular irritation to vision loss. The initial diagnosis is based on clinical findings and laboratory tests. Orbital imaging, such as magnetic resonance imaging (MRI) and computed tomography (CT), is an important tool to assess orbital changes, being also useful for understanding disease progression and surgical planning. In this narrative review, we included 92 studies published from 1979 to 2020 that used either MRI and/or CT to diagnose and investigate GO, proposing new methods and techniques. Most of the methods used still need to be corroborated and validated, and, despite the different methods and approaches for thyroid eye disease (TED) evaluation, there is still a lack of standardization of measurements and outcome reports; therefore, additional studies should be performed to include these methods in clinical practice, facilitating the diagnosis and approach for the treatment of TED.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10801040PMC
http://dx.doi.org/10.3389/fendo.2023.1277961DOI Listing

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