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http://dx.doi.org/10.3389/fnagi.2023.1352988 | DOI Listing |
Ann Oncol
February 2025
Université Libre de Bruxelles (ULB), Brussels, Belgium; Department of Medical Oncology, Hôpital Universitaire de Bruxelles (HUB), Institut Jules Bordet, Brussels, Belgium. Electronic address:
Urologia
January 2025
Department of Medicine and Translational Surgery, Università Cattolica del Sacro Cuore, Rome, Italy.
Front Pharmacol
January 2025
Institute of Pharmaceutical Chemistry, Goethe University, Frankfurt, Germany.
5-Lipoxygenase (5-LO), encoded by the gene , is implicated in several pathologies. As key enzyme in leukotriene biosynthesis, 5-LO plays a central role in inflammatory diseases, but the 5-LO pathway has also been linked to development of certain hematological and solid tumor malignancies. Of note, previous studies have shown that the leukemogenic fusion protein MLL-AF4 strongly increases gene promoter activity.
View Article and Find Full Text PDFArch Endocrinol Metab
November 2024
Universidade de São Paulo São PauloSP Brasil Universidade de São Paulo, Fisiologia e Biofísica, São Paulo, SP, Brasil.
Eur Radiol
January 2025
Department of Radiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
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