This paper presents the first nickel-plated micro-Coriolis mass-flow sensor with integrated optical readout. The sensor consists of a freely suspended tube made of electroplated nickel with a total length of 60 mm, an inner diameter of 580 µm, and a wall thickness of approximately 8 µm. The U-shaped tube is actuated by Lorentz forces. An optical readout consisting of two LEDs and two phototransistors is used to detect the tube motion. Mass-flow measurements were performed at room temperature with water and isopropyl alcohol for flows up to 200 g/h and 100 g/h, respectively. The measured resonance frequencies were 1.67 kHz and 738 Hz for water and 1.70 kHz and 752 Hz for isopropyl alcohol for the twist and swing modes, respectively. The measured phase shift between the two readout signals shows a linear response to mass flow with very similar sensitivities for water and isopropyl alcohol of 0.41mdegg/h and 0.43 mdegg/h, respectively.
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http://dx.doi.org/10.3390/mi15010114 | DOI Listing |
Anal Chem
January 2025
Department of Applied Chemistry, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
The integration of barcode technology with smartphones on paper-based analytical devices (PADs) presents a promising approach to bridging manual detection with digital interpretation and data storage. However, previous studies of 1D barcode approaches have been limited to providing only a "yes/no" response for analyte detection. Herein, a method of using barcode readout for semiquantitative signal detection on PADs has been achieved through the integration of barcode technology with a distance-based measurement concept on PADs.
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January 2025
Institute of Translational Medicine, Department of Health Sciences and Technology, ETH Zürich, 8092 Zürich, Switzerland.
Proteases, an important class of enzymes that cleave proteins and peptides, carry a wealth of potentially useful information. Devices to enable routine and cost effective measurement of their activity could find frequent use in clinical settings for medical diagnostics, as well as some industrial contexts such as detecting on-line biological contamination. In particular, devices that make use of readouts involving magnetic particles may offer distinct advantages for continuous sensing because material they release can be magnetically captured downstream and their readout is insensitive to optical properties of the sample.
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January 2025
School of Physics and Astronomy, University of Glasgow, Glasgow, United Kingdom.
SPDC photon-pairs exhibit spatial correlations which can be measured using detector arrays sensitive to single photons. However, these detector arrays have multiple readout modes and in order to optimise detection it is important to select the optimum mode to detect the correlations against a background of optical and electronic noise. These quantum correlations enable applications in imaging, sensing, communication, and optical processing.
View Article and Find Full Text PDFFoods
December 2024
Key Laboratory of Tropical Fruit and Vegetable Cold-Chain of Hainan Province, Institute of Agro-Products of Processing and Design, Hainan Academy of Agricultural Sciences, Haikou 571100, China.
Multicolor immunoassay is a powerful tool for rapid analysis without the use of bulky instruments owing to various color conversions, which is suitable for on-site visual analysis for pesticides. Herein, this study developed a multicolor immunoassay for the rapid detection of isocarbophos. After competitive immunoassay, the secondary antibody (GAM-ALP) catalyzed ascorbyl-2-phosphate (AAP) into ascorbic acid (AA).
View Article and Find Full Text PDFACS Sens
January 2025
School of Materials Science and Engineering, Guangzhou Key Laboratory of Flexible Electronic Materials and Wearable Devices, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, State Key Laboratory of Optoelectronic Materials and Technologies, Sun Yat-sen University, Guangzhou 510275, People's Republic of China.
Steroid hormones, especially progesterone (P), estradiol (E), and testosterone (T), are key bioactive regulators in various female physiological processes, including growth and development, ovulation, and the reproductive cycle, as well as metabolism and mental health. As lipophilic molecules produced in sex glands, these steroid female hormones can be transported through blood vessels into various body fluids such as saliva, sweat, and urine. However, the ultralow concentration of steroid hormones down to picomolar (pM) level necessitates great demands for ultrasensitive but low-cost analytic tools to implement accurate, point-of-care or even continuous monitoring in a user-friendly fashion.
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