This paper presents a home-built projection lithographer designed to transfer the image from a DLP (digital light processing) projector MEMS matrix onto the microscope objective's field of view, where a photoresist-covered substrate is placed. The photoresist is exposed using blue light with a wavelength of 450 nm. To calibrate the device and adjust focal lengths, we utilize a red light that does not affect the photoresist. The substrate is located on a movable platform, allowing the exposure field to be shifted, enabling the exposure of designs with lateral sizes of 1 × 1 cm2 at a resolution of a few micrometers. Our setup showcases a 2 μm resolution for the single frame 200 × 100 μm2, and a 5 μm resolution for 1 × 1 cm2 with field stitching. The exposure speed, approximately 1 mm2/100 s, proves to be sufficient for a variety of laboratory prototyping needs. This system offers a significant advantage due to its utilization of easily accessible and budget-friendly components, thereby enhancing its accessibility for a broader user base. The exposure speed and resolution meet the requirements for laboratory prototyping in the fields of 2D materials, quantum optics, superconducting microelectronics, microfluidics, and biology.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11154530 | PMC |
http://dx.doi.org/10.3390/mi15010039 | DOI Listing |
Circ Cardiovasc Interv
December 2024
Canadian VIGOUR Centre (K.R.B., R.C.W., Y.Z., T.T., E.L., C.M.W., P.W.A.), University of Alberta, Edmonton, Canada.
Background: In STREAM-1 (Strategic Reperfusion Early After Myocardial Infarction), excess intracranial hemorrhage occurred in patients aged ≥75 years receiving full-dose tenecteplase as part of a pharmaco-invasive strategy, whereas no further intracranial hemorrhage occurred after halving the tenecteplase dose. In STREAM-2 (Second Strategic Reperfusion Early After Myocardial Infarction), half-dose tenecteplase was an effective and safe pharmaco-invasive strategy in older patients with ST-segment-elevation myocardial infarction presenting within <3 hours, compared with primary percutaneous coronary intervention (PCI). We prespecified evaluating the efficacy and safety of a half-dose versus full-dose pharmaco-invasive strategy and compared the half-dose pharmaco-invasive strategy to primary PCI in patients aged ≥75 years.
View Article and Find Full Text PDFInvest Radiol
August 2024
From the Department of Radiology, Balgrist University Hospital, Zurich, Switzerland (A.A.M., G.C.F., R.S.); Swiss Center for Musculoskeletal Imaging, Balgrist Campus AG, Zurich, Switzerland (A.A.M., D.N.); Department of Orthopedic Surgery, Balgrist University Hospital, Zurich, Switzerland (F.W.); and Medical Faculty, University of Zurich, Zurich, Switzerland (D.N., R.S.).
Nat Commun
August 2024
Institut Langevin, ESPCI Paris, PSL University, CNRS, 75005, Paris, France.
As light travels through a disordered medium such as biological tissues, it undergoes multiple scattering events. This phenomenon is detrimental to in-depth optical microscopy, as it causes a drastic degradation of contrast, resolution and brightness of the resulting image beyond a few scattering mean free paths. However, the information about the inner reflectivity of the sample is not lost; only scrambled.
View Article and Find Full Text PDFInvest Radiol
December 2024
From the Swiss Center for Musculoskeletal Imaging, Balgrist Campus AG, Zurich, Switzerland (A.A.M., C.v.D., S.S., D.N.); Department of Radiology, Balgrist University Hospital, Zurich, Switzerland (A.A.M., G.C.F., S.S.G., R.S.); Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Zurich, Switzerland (C.v.D., S.S.); and Medical Faculty, University of Zurich, Zurich, Switzerland (R.S., D.N.).
Objectives: The aim of this study was to compare the image quality of 7 T turbo spin echo (TSE) knee images acquired with varying factors of parallel-imaging acceleration reconstructed with deep learning (DL)-based and conventional algorithms.
Materials And Methods: This was a prospective single-center study. Twenty-three healthy volunteers underwent 7 T knee magnetic resonance imaging.
Invest Radiol
November 2024
From the Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD (F.H., F.D.F., P.Y., M.N., M.D., R.G., E.C.J., E.B.T., A.A.M.); Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (N.G., M.W.B., W.M.L.); Siemens Healthineers, Malvern, PA (P.S.); Department of Radiology, University of Alabama at Birmingham, Birmingham, AL (M.N.); Laboratory of Imaging Physics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (M.W., H.W.); and Center for Interventional Oncology, Radiology, and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, (W.F.P.).
Objectives: The aim of this study was to assess the interreader reliability and per-RCC sensitivity of high-resolution photon-counting computed tomography (PCCT) in the detection and characterization of renal masses in comparison to MRI.
Materials And Methods: This prospective study included 24 adult patients (mean age, 52 ± 14 years; 14 females) who underwent PCCT (using an investigational whole-body CT scanner) and abdominal MRI within a 3-month time interval and underwent surgical resection (partial or radical nephrectomy) with histopathology (n = 70 lesions). Of the 24 patients, 17 had a germline mutation and the remainder were sporadic cases.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!