In Vitro Analysis of the Antagonistic Biological and Chemical Interactions between the Endophyte and the Phytopathogen .

Int J Mol Sci

Departamento de Biomedicina, Biotecnología y Salud Pública, Área de Microbiología, Facultad de Ciencias del Mar y Ambientales, Universidad de Cádiz, Puerto Real, 11510 Cadiz, Spain.

Published: January 2024

Plant pathogenic infections causing substantial global food losses are a persistent challenge. This study investigates a potential biocontrol strategy against the necrotrophic fungus using the endophytic fungus isolated from in Colombia. Today, synthetic fungicides dominate control, raising environmental and health concerns. exhibits notable in vitro effects, inhibiting growth by approximately 60% during co-culture and 50% in double disc co-culture. Additionally, it suppresses botryanes production and produces the compound heptacyclosordariolone, which has proven effective in inhibiting mycelial growth and spore germination in vitro. This biocontrol agent could be a potential eco-friendly alternative to replace synthetic fungicides. Our study provides insights into the chemical and biological mechanisms underpinning the antagonistic activity of , emphasizing the need for further research to understand its biosynthesis pathways and optimize its biocontrol potential. It also contributes molecular evidence of fungal interactions with implications for advanced forums in molecular studies in biology and chemistry, particularly in addressing plant pathogenic infections and promoting sustainable agriculture.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10816056PMC
http://dx.doi.org/10.3390/ijms25021022DOI Listing

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