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Importance of early use of tolvaptan in hyponatremic acutely decompensated heart failure patients, a retrospective study.
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Department of Cardiology, Division of Heart & Lungs, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands.
Background: Hyponatremia is one of the complicating findings in acute decompensated heart failure. Decrease in cardiac output and systemic blood pressure triggers activation of renin-angiotensin-aldosterone system, antidiuretic hormone, and norepinephrine due to the perceived hypovolemia. Fluid-overloaded heart failure patients are commonly treated with loop diuretics, acutely decompensated heart failure patients tend to be less responsive to conventional oral doses of a loop diuretic, while other different diuretics could work in different part of nephron circulation system.
View Article and Find Full Text PDFThe Future of Parenthood? Examining the Promise and Complexity of Pregnancy Robots in Reproductive Health.
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Department of Pharmacology, MGM Medical College & Hospital, MGM Institute of Health Sciences (MGMIHS), Nerul, Navi Mumbai, 400706, India.
Advancements in reproductive technology are now approaching an unprecedented frontier: the pregnancy robot, a potential artificial womb capable of carrying a fetus from fertilization to birth. This innovation, by simulating the natural uterine environment, could redefine pregnancy and parenthood, offering transformative benefits for maternal and infant health. The pregnancy robot promises safer pathways for individuals with medical risks, LGBTQ + couples, and single parents, while also reducing the risks of complications like preeclampsia and preterm birth.
View Article and Find Full Text PDFLetter to the Editor Regarding: Haddad, A., Suter, M., Greve, J.W. et al. Therapeutic Options for Recurrence of Weight and Obesity Related Complications After Metabolic and Bariatric Surgery: An IFSO Position Statement. OBES SURG 34, 3944-3962 (2024). https://doi.org/10.1007/s11695-024-07489-7.
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Torsby Hospital, Torsby, SE, Sweden.
Weight loss specific to indication, remission of diabetes, and short-term complications after sleeve gastrectomy conversion to Roux-en-Y gastric bypass: a systematic review and meta-analysis.
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Optimization of FRET imaging in Arabidopsis Protoplasts.
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Department of Integrated Biological Science, College of Natural Sciences, Pusan National University, Busan 46241, Republic of Korea; Department of Biological Sciences, College of Natural Sciences, Pusan National University, Busan 46241, Republic of Korea; Institute of Systems Biology, Pusan National University, Busan 46241, Republic Korea. Electronic address:
Recent advancements in fluorescence-based biosensor technologies have enabled more precise and accurate Förster Resonance Energy Transfer (FRET) imaging within Agrobacterium-mediated plant transformation systems. However, the application of FRET imaging in plant tissues remains hindered by significant challenges, particularly the time-intensive process of generating transgenic lines and the complications arising from tissue autofluorescence. In contrast, protoplast-based FRET imaging offers a rapid and efficient platform for functional screening and analysis, making it an essential tool for plant research.
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