Three-dimensional (3D) shape lies at the core of understanding the physical objects that surround us. In the biomedical field, shape analysis has been shown to be powerful in quantifying how anatomy changes with time and disease. The Shape AnaLysis Toolbox (SALT) was created as a vehicle for disseminating advanced shape methodology as an open source, free, and comprehensive software tool. We present new developments in our shape analysis software package, including easy-to-interpret statistical methods to better leverage the quantitative information contained in SALT's shape representations. We also show SlicerPipelines, a module to improve the usability of SALT by facilitating the analysis of large-scale data sets, automating workflows for non-expert users, and allowing the distribution of reproducible workflows.
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http://dx.doi.org/10.1007/978-3-031-46914-5_16 | DOI Listing |
PLoS One
January 2025
School of Foreign Languages, Central South University, Changsha, Hunan, China.
The dissemination of sustainable development concepts in large international events like the Olympics has garnered great attention. As a major international sports event, the Beijing Winter Olympics served as an important platform for showcasing China's sustainable development philosophy through its official news coverage. In this context, metaphor, as a powerful cognitive tool, plays a crucial role in shaping public perception and facilitating the dissemination of values by mapping concrete source domains onto abstract target domains.
View Article and Find Full Text PDFPLoS Comput Biol
January 2025
Department of Mechanical Engineering, University of California Riverside, Riverside, California, United States of America.
Respiratory diseases represent a significant healthcare burden, as evidenced by the devastating impact of COVID-19. Biophysical models offer the possibility to anticipate system behavior and provide insights into physiological functions, advancements which are comparatively and notably nascent when it comes to pulmonary mechanics research. In this context, an Inverse Finite Element Analysis (IFEA) pipeline is developed to construct the first continuously ventilated three-dimensional structurally representative pulmonary model informed by both organ- and tissue-level breathing experiments from a cadaveric human lung.
View Article and Find Full Text PDFMicrosc Microanal
January 2025
Vocational School of Health Services, Ankara Yıldırım Beyazıt University, Çubuk, Ankara 06760, Turkey.
Leeches are widely used as model organisms in scientific studies and medical treatments. Medical leeches are hematophagous parasites that usually feed on the blood of their hosts. Some leeches show deformities, usually after feeding.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
January 2025
TU Dortmund University, Faculty for Chemistry and Chemical Biology, Otto-Hahn-Str. 6, 44227, Dortmund, GERMANY.
Precise control over the catenation process in interlocked supramolecular systems remains a significant challenge. Here, we report a system in which a lantern-shaped Pd2L4 cage can dimerize to form two distinct Pd4L8 catenanes with different interlocking degree: a previously described quadruply interlocked double cage motif of D4 symmetry and an unprecedented triply interlocked structure of C2h symmetry. While the former structure features a linear arrangement of four Pd(II) centers, separated by three mechanically linked pockets, the new motif has a staggered shape.
View Article and Find Full Text PDFEur J Popul
January 2025
School of Social Sciences, University of Iceland, Reykjavík, Iceland.
In 2021, during the height of the COVID-19 pandemic, the Total Fertility Rate in Iceland rose unexpectedly from 1.79 to 1.90.
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