AI Article Synopsis
- Systemic lupus erythematosus (SLE) is an autoimmune disease that can present with varied symptoms, particularly more atypical ones in children compared to adults.
- A rare case is highlighted involving a young boy with SLE who also suffered from Fanconi syndrome and renal tubular acidosis, leading to significant health issues like weakness and malnutrition.
- The child was successfully treated with a combination of medications, including corticosteroids and mycophenolate mofetil, and the report emphasizes the need for awareness of atypical SLE in pediatric cases to prevent diagnostic errors.
Article Abstract
Background: Systemic lupus erythematosus is an autoimmune disease with diverse clinical manifestations. The symptoms of SLE in children are more atypical than adults. Childhood SLE complicated with Fanconi syndrome is extremely rare and even more difficult to diagnose.
Case Presentation: This article reports a preschool boy with SLE who presented with renal tubular acidosis, accompanied by weakness in both lower limbs, delayed growth, and malnutrition. It was later found that the patient had the complication of Fanconi syndrome with renal tubular acidosis. Ultimately, renal biopsy confirmed lupus nephritis. The patient was treated with corticosteroid combined with mycophenolate mofetil, hydroxychloroquine, and belimumab. The symptoms of the child were relieved.
Conclusion: Here we report an extremely rare case of childhood SLE complicated with Fanconi syndrome. There has been no similar clinical report. It is necessary to be alert to the possibility of atypical SLE in children to avoid missed diagnosis and misdiagnosis.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10796690 | PMC |
| http://dx.doi.org/10.3389/fped.2023.1230366 | DOI Listing |
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