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Estimating the economic impact of complications after open tibial fracture: A secondary analysis of the pilot Gentamicin Open Tibia trial (pGO-Tibia). | LitMetric

AI Article Synopsis

  • - The study aimed to assess the indirect economic impact of tibial fractures and related adverse events (AEs), such as infections and nonunion, in Tanzania, focusing on their effects on work productivity and household costs.
  • - Conducted at the Muhimbili Orthopaedic Institute, the research involved 100 adults with open tibial shaft fractures and compared work hours and costs associated with AEs, revealing that those with AEs faced significantly lower rates of returning to work and higher productivity losses.
  • - Findings indicated that the average indirect cost for patients with AEs was $2,385, which represented 92% of their annual income, highlighting a considerable financial burden and more difficulty in managing household expenses after injury compared to those without A

Article Abstract

Objectives: To estimate the indirect economic impact of tibial fractures and their associated adverse events (AEs) in Tanzania.

Design: A secondary analysis of the pilot Gentamicin Open (pGO)-Tibia randomized control trial estimating the indirect economic impact of suffering an AE, defined as a fracture-related infection (FRI) and/or nonunion, after an open tibial fracture in Tanzania.

Setting: The pGO-Tibia trial was conducted from November 2019 to August 2021 at the Muhimbili Orthopaedic Institute in Dar es Salaam, Tanzania.

Patients/participants: One hundred adults with open tibial shaft fractures participated in this study.

Intervention: Work hours were compared between AE groups. Cost data were analyzed using a weighted-average hourly wage and converted into purchasing power parity-adjusted USD.

Main Outcome Measurements: Indirect economic impact was analyzed from the perspective of return to work (RTW), lost productivity, and other indirect economic and household costs. RTW was analyzed using a survival analysis.

Results: Half of patients returned to work at 1-year follow-up, with those experiencing an AE having a significantly lower rate of RTW. Lost productivity was nearly double for those experiencing an AE. There was a significant difference in the mean outside health care costs between groups. The total mean indirect cost was $2385 with an AE, representing 92% of mean annual income and an increase of $1195 compared with no AE. There were significantly more patients with an AE who endorsed difficulty affording household expenses postinjury and who borrowed money to pay for their medical expenses.

Conclusions: This study identified serious economic burden after tibial fractures, with significant differences in total indirect cost between those with and without an AE.

Level Of Evidence: II.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10798688PMC
http://dx.doi.org/10.1097/OI9.0000000000000290DOI Listing

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