ACS Appl Mater Interfaces
National Engineering Research Center for Biomaterials, Sichuan University, 29# Wangjiang Road, Chengdu, Sichuan 610064, P. R. China.
Published: January 2024
Sharply rising oxidative stress and ineffectual angiogenesis have imposed restrictions on diabetic wound healing. Here, a photothermal-responsive nanodelivery platform (HHC) was prepared by peroxidase (CAT)-loaded hollow copper sulfide dispersed in photocurable methacrylamide hyaluronan. The HHC could scavenge reactive oxygen species (ROS) and promote angiogenesis by photothermally driven CAT and Cu release. Under near-infrared light irradiation, the HHC presented safe photothermal performance (<43 °C), efficient bacteriostatic ability against and . It could rapidly release CAT into the external environment for decomposing HO and oxygen generation to alleviate oxidative stress while promoting fibroblast migration and VEGF protein expression of endothelial cells by reducing intracellular ROS levels. The nanodelivery platform presented satisfactory therapeutic effects on murine diabetic wound healing by modulating tissue inflammation, promoting collagen deposition and increasing vascularization in the neodermis. This HHC provided a viable strategy for diabetic wound dressing design.
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http://dx.doi.org/10.1021/acsami.3c15593 | DOI Listing |
Environ Pollut
January 2025
Fujian Provincial Key Laboratory for Coastal Ecology and Environmental Studies, State Key Lab of Marine Environmental Science, College of the Environment and Ecology, Xiamen University, Xiamen, Fujian 361102, China. Electronic address:
A major proportion of metal contaminants in aquatic environments is bound to suspended particulate matter (SPM), yet environmental monitoring typically focuses on dissolved metals, with the filtration step removing SPM. This step may inadvertently hide the potential risks posed by particulate metals. In this study, we used stable isotope tracers to quantify the contributions of SPM-bound metals to the bioaccumulation of nickel (Ni), copper (Cu), zinc (Zn), cadmium (Cd), and lead (Pb) in Ruditapes philippinarum, a widely distributed clam crucial to global aquaculture.
View Article and Find Full Text PDFAnal Chim Acta
February 2025
College of Food Science and Technology, Henan Key Laboratory of Cereal and Oil Food Safety Inspection and Control, Henan University of Technology, Zhengzhou, 450001, China.
Background: Aflatoxin B1 (AFB1) is a secondary metabolite produced by Aspergillus flavus and Aspergillus parasiticus. This toxin is highly carcinogenic and toxic, posing a serious threat to human and animal health. AFB1 primarily enters the human body through contaminated food, particularly peanuts, corn, nuts, and wheat.
View Article and Find Full Text PDFACS Appl Bio Mater
January 2025
School of Pharmacy, Shenyang Key Laboratory of Functional Drug Carrier Materials, Shenyang Pharmaceutical University, Shenyang 110016, China.
A multifunctional nanoplatform integrating multiple therapeutic functions may be an effective strategy to realize satisfactory therapeutic efficacy in the treatment of tumors. However, there is still a certain challenge in integrating multiple therapeutic agents into a single formulation using a simple method due to variations in their properties. In this work, multifunctional CuS-ICG@PDA-FA nanoparticles (CIPF NPs) with excellent ability to produce reactive oxygen species and photothermal conversion performance are fabricated by a simple and gentle method.
View Article and Find Full Text PDFChemSusChem
January 2025
Dalian University of Technology, State Key Laboratory of Fine Chemicals, 2 Ligong Rd., 116024, Dalian, CHINA.
Understanding the impact of surface copper valence states on the distribution of electrochemical carbon dioxide products is critical. Herein, CuO@Cu2O with a Cu2+/Cu+ interface was fabricated using wet chemical etching approach. The hollow shape offered a large region for gas adsorption, while the interfacial mixed chemical state of Cu2+/Cu+ with tunable control ratio raised the local density of CHO* and accelerated the carbon-carbon coupling reaction.
View Article and Find Full Text PDFNanoscale
January 2025
CNR - Istituto Nanoscienze, Modena, Italy.
Copper nanoparticles (NPs) can be coupled with cuprous oxide, combining photoelectrocatalytic properties with a broad-range optical absorption. In the present study, we aimed to correlate changes in morphology, electronic structure and plasmonic properties of Cu NPs at different stages of oxidation. We demonstrated the ability to monitor the oxidation of NPs at the nanometric level using STEM-EELS spectral maps, which were analyzed with machine learning algorithms.
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