Design patterns of biological cells.

Bioessays

Department of Bioengineering, University of Washington, Seattle, Washington, USA.

Published: March 2024

AI Article Synopsis

  • Design patterns are general solutions to common problems, originally created by architects and computer scientists for better design abstraction.
  • This text applies design patterns to cell biology, categorizing them into creational, structural, and behavioral patterns related to cell reaction networks.
  • The approach offers new insights into various biological systems, including the E. coli central metabolic network and yeast pheromone response signaling.

Article Abstract

Design patterns are generalized solutions to frequently recurring problems. They were initially developed by architects and computer scientists to create a higher level of abstraction for their designs. Here, we extend these concepts to cell biology to lend a new perspective on the evolved designs of cells' underlying reaction networks. We present a catalog of 21 design patterns divided into three categories: creational patterns describe processes that build the cell, structural patterns describe the layouts of reaction networks, and behavioral patterns describe reaction network function. Applying this pattern language to the E. coli central metabolic reaction network, the yeast pheromone response signaling network, and other examples lends new insights into these systems.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10922931PMC
http://dx.doi.org/10.1002/bies.202300188DOI Listing

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