Tularemia is a rare disease but shows an approximately 10-fold increase in reported cases over the last 15 years in Germany. Clinical symptoms of acute tularemia infection are various, which often delays diagnosis. This case report gives an overview of the clinical manifestations of acute tularemia and shows the importance of interdisciplinary work to shorten the time from the onset of symptoms to effective treatment in infection with . Since some cases of tularemia are life-threatening, early diagnosis is vital. This case report serves as a reminder that rare diseases need to be considered in cervical lymphadenopathy.

Download full-text PDF

Source
http://dx.doi.org/10.1177/01455613231226046DOI Listing

Publication Analysis

Top Keywords

acute tularemia
8
case report
8
tularemia
5
rare case
4
case tularemia
4
tularemia preauricular
4
preauricular lymphadenopathy
4
lymphadenopathy conjunctivitis
4
conjunctivitis 27-year-old
4
27-year-old male
4

Similar Publications

Development of a Real-Time PCR Assay for the Detection of spp. and the Identification of subsp. .

Microorganisms

November 2024

Institute for Integrative Biology of the Cell (I2BC), Centre National de la Recherche Scientifique (CNRS), Commissariat à l'Énergie Atomique (CEA), Université Paris-Saclay, 91198 Gif-sur-Yvette, France.

Article Synopsis
  • - Tularemia is an infectious disease that requires ongoing monitoring of both human and animal cases, along with tracking the pathogen in natural environments to effectively prevent and control outbreaks.
  • - The disease is caused by a bacterium with three different subspecies, and researchers have created a new real-time PCR test that can accurately detect these subspecies and identify where they’re spreading.
  • - The new PCR assay has been rigorously tested for accuracy and sensitivity, with very low limits of detection, enhancing tularemia surveillance efforts in Kazakhstan by allowing for direct detection of the pathogen in various samples.
View Article and Find Full Text PDF

Molecular investigation of Coxiella burnetii, Brucella spp., Ehrlichia spp., and Borrelia spp. among patients suspected of having Crimean-Congo Hemorrhagic Fever in Iran.

J Infect Public Health

December 2024

Department of Epidemiology and Biostatics, Pasteur Institute of Iran, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Tehran, Iran; Student Research Committee, Pasteur Institute of Iran, Tehran, Iran; National Reference Laboratory for Plague, Tularemia and Q Fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Akanlu, KabudarAhang, Hamadan, Iran. Electronic address:

Article Synopsis
  • The study focuses on Crimean-Congo Hemorrhagic Fever (CCHF), which is a tick-borne viral disease, and aims to examine the presence of specific bacterial infections among individuals who are suspected of having CCHF in Iran.
  • Researchers analyzed 260 serum samples from patients who tested negative for CCHF virus, finding 3.46% positive for brucellosis and 3.07% for Q fever, while no borreliosis or ehrlichiosis cases were detected.
  • The findings suggest that bacterial infections like brucellosis and Q fever should be considered when diagnosing CCHF, and further broad investigations into bacterial infections with similar symptoms are recommended.
View Article and Find Full Text PDF
Article Synopsis
  • - The study aimed to analyze clinical features in cats diagnosed with tularemia, comparing those with and without the disease and identifying factors that increase the chance of a tularemia diagnosis.
  • - Through the analysis of medical records from 2000 to 2021, the research found that affected cats were mostly middle-aged male domestic shorthairs with outdoor access, often presenting symptoms like lethargy, anorexia, and fever, among other findings.
  • - Key results indicated that leukopenia and neutropenia were significantly more common in cats with positive PCR tests for tularemia, suggesting that these blood abnormalities can be important indicators of the disease.
View Article and Find Full Text PDF
Article Synopsis
  • Hemophagocytic lymphohistiocytosis (HLH) is a rare and severe immune disorder that is hard to diagnose due to its varied causes and symptoms, often requiring intense medical care.
  • HLH can either be genetic (HLH syndrome) or acquired (HLH disease), triggered by instances like infections, autoimmune diseases, or cancers; this case study presents the first known instance of HLH caused by tularemia in an older female patient.
  • The patient was initially treated for suspected malignancy but switched to antimicrobial therapy after testing positive for tularemia, leading to a lengthy recovery period but ultimately highlighting the need for quick identification of triggering infections for more effective HLH treatment.
View Article and Find Full Text PDF
Article Synopsis
  • Acute focal lymphadenitis in humans can occasionally be caused by zoonotic pathogens, which are transmitted without direct contact with infected animals, often via vectors.
  • The text highlights various zoonotic diseases associated with lymphadenitis, including tularemia, plague, and rickettsioses, and summarizes their clinical signs, diagnosis, and treatment options.
  • It recommends a combined antibiotic therapy for severe cases and emphasizes the need for a "one health approach" to enhance clinical outcomes and the understanding of these rare conditions.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!