Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.kint.2023.08.015 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Efficacy and Safety of Sodium Zirconium Cyclosilicate in the Management of Hyperkalemia in Patients with Heart Failure with Reduced and Mildly Reduced Ejection Fraction and Chronic Kidney Disease Treated with Spironolactone: rational for and design of the REGISTA-K trial.
J Card Fail
December 2024
Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan. Electronic address:
Background: To evaluate whether sodium zirconium cyclosilicate (SZC) enables the uptitration of spironolactone without increasing the risk of hyper- and hypokalemia in patients with heart failure with reduced and mildly reduced ejection fraction (HFrEF and HFmrEF) and moderate/severe chronic kidney disease (CKD) who developed hyperkalemia during treatment with suboptimal spironolactone dose.
Methods: The REGISTA-K is a randomized, double-blind, placebo-controlled, multicenter trial that examined the efficacy and safety of SZC in uptitrating spironolactone without the occurrence of hyperkalemia or hypokalemia. A total of 266 patients with HFrEF and HFmrEF and hyperkalemia will be randomized in a 1:1 ratio to receive either SZC or placebo after treating hyperkalemia with SZC at 25 sites in Japan.
Inductively coupled plasma mass spectrometry was employed to determine the content of 25 inorganic elements in Bambusae Concretio Silicea, and the elemental fingerprint was established according to the element content. SPSS 20.0 and SIMCA 14.
View Article and Find Full Text PDFEffect of Acidulated Phosphate Fluoride Gel on Zirconia Intaglio Surface: An Study.
J Int Soc Prev Community Dent
October 2024
Department of Basic Dental Science, College of Dentistry, University of Mosul, Mosul, Iraq.
Aim: To evaluate the micro-shear bond strength (µ-SBS) of resin-modified glass ionomer cement and to assess the chemical and topographical changes in the zirconia fitting surface induced by acidulated phosphate fluoride (APF) gel using scanning electron microscope (SEM) analysis and Fourier transform infrared (FTIR) spectroscopy.
Materials And Methods: Thirty-two samples were prepared from two zirconia materials, UPCERA HT White and BruxZir Solid Zirconia, milled by a computer-aided design/computer-aided manufacturing system. From each zirconia sample, six plates were prepared for FTIR and SEM testing.
Assessment of a Light-Curable Hydrogel to Be Used for Root Canal Obturation.
J Dent Res
December 2024
Dentistry, School of Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK.
Root canal obturation involves filling of the chemomechanically prepared root canal space. Despite reduced microbial load, residual bacteria can still lead to reinfection and treatment failure. Currently, obturation techniques use a combination of gutta-percha and sealer, which requires the preparation of the root canal to specific sizes and tapers to enable the fitting of customized cones.
View Article and Find Full Text PDFSodium zirconium cyclosilicate treatment and rates of emergency interventions for hyperkalaemia: a propensity-score weighted case-control study.
Clin Kidney J
November 2024
School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Background: Sodium zirconium cyclosilicate (SZC) reduces serum potassium in patients with chronic hyperkalaemia in clinical trials, but its role in the emergency treatment of hyperkalaemia is unproven. We hypothesized that SZC use for emergent hyperkalaemia would be associated with a reduction in rates of emergency interventions for hyperkalaemia.
Methods: This was a single-centre, propensity score-weighted case-control study of patients admitted with hyperkalaemia to a specialist renal centre.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!