The concept of Formal Thought Disorder (FTD) is an ambiguous and disputed one, even though it has endured as a core psychopathological construct in clinical Psychiatry. FTD can be summarized as a multidimensional construct, reflecting difficulties or idiosyncrasies in thinking, language, and communication in general and is usually subdivided into positive negative. In this article, we aim to explore the putative neurobiology of FTD, ranging from changes in neurotransmitter systems to alterations in the functional anatomy of the brain. We also discuss recent critiques of the operationalist view of FTD and how they might fit in its biological underpinnings. We conclude that FTD might be the observable phenotype of many distinct underlying alterations in different proportions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2174/0115680266272521240108102354 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Maternal Cannabis Use During Pregnancy and Neuropsychiatric Adverse Outcomes During Childhood and Early Adult Life.
J Clin Psychiatry
January 2025
Department of Psychiatry, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India, Department of Clinical Psychopharmacology and Neurotoxicology, National Institute of Mental Health and Neurosciences, Bangalore, India
Cannabis use during pregnancy is increasing; the study of adverse outcomes in cannabis-exposed pregnancies is therefore important. Previous articles in this series described increased risks of maternal adverse outcomes, fetal adverse outcomes, birth defects in newborns, and autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) in childhood. This article examines neuropsychiatric adverse outcomes in offspring gestationally exposed to cannabis.
View Article and Find Full Text PDFBackground: It is high time we acknowledged that the IT industry will determine our destiny given its rapid development. The demand to use smartphones and other forms of technology into healthcare is growing in tandem with the population. A great deal has been accomplished because of developments in computer science.
View Article and Find Full Text PDFBackground: Healthcare professionals face numerous challenges regarding the delivery of care. Creating solutions to these challenges is imperative to improve the quality and safety of care to positively impact patient outcomes. However, health professional students rarely receive formal training regarding systems thinking during didactic components of their professional training.
View Article and Find Full Text PDFFormal Thought Disorder in Schizophrenia: A Problematic History.
Schizophr Bull
January 2025
Department of Psychiatry, University of Oxford, and Oxford Health NHS Foundation Trust, Warneford Hospital, Warneford Lane, Oxford, OX37JX, United Kingdom.
Background And Hypothesis: Formal thought disorder (FTD), studied even before the inception of the concept of schizophrenia, remains a deeply isolating experience for patients as well as a difficult one for their interlocutors, including clinicians.
Study Design: The views on language, paralinguistic, and extralinguistic features exhibited by patients with severe mental ill health are reviewed, including the contributions from 19th-century European authors to the last third of the 20th century.
Study Results: Stages in the construction of FTD are described, including its merging with Dementia Praecox, and its subsequently being shaped by notions such as primitive archaic thinking, paralogical or autistic thinking, concretism, overinclusive thinking, and the return of the efforts to describing it with increased reliability.
Establishing a Successful Research Infrastructure for Orthopaedic Surgery Residents.
J Am Acad Orthop Surg
January 2025
Research among orthopaedic surgery residents provides numerous benefits, which include but are not limited to development of critical thinking skills, greater understanding of study design and statistical analysis, strengthened fellowship applications, networking, and the ability to practice evidence based medicine. Research has been increasingly emphasized among orthopaedic surgery residency directors, and residency programs have uniformly implemented protected research time into their formal clinical training. Despite this, there are few resources describing the ability to conduct research effectively during residency.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!