AI Article Synopsis

  • - Genetically modified maize DP23211 was engineered to resist specific pests and tolerate a certain herbicide, with no critical safety issues found in molecular and bioinformatic analyses.
  • - Differences in nutrient levels were noted but did not pose safety or nutritional concerns, and the GMO Panel deemed the new proteins and RNA from the modification to be safe for consumption.
  • - Overall, maize DP23211 is considered just as safe for human and animal health as conventional maize, and no additional monitoring for safety or environmental impact is required.

Article Abstract

Genetically modified maize DP23211 was developed to confer control of certain coleopteran pests and tolerance to glufosinate-containing herbicide. These properties were achieved by introducing the , , and expression cassettes. The molecular characterisation data and bioinformatic analyses do not identify issues requiring food/feed safety assessment. None of the identified differences in the agronomic/phenotypic and compositional characteristics tested between maize DP23211 and its conventional counterpart needs further assessment, except for those in levels of histidine, phenylalanine, magnesium, phosphorus and folic acid in grain, which do not raise safety and nutritional concerns. The GMO Panel does not identify safety concerns regarding the toxicity and allergenicity of the IPD072Aa, PAT and PMI proteins and the DvSSJ1 dsRNA and derived siRNAs newly expressed in maize DP23211, and finds no evidence that the genetic modification impacts the overall safety of maize DP23211. In the context of this application, the consumption of food and feed from maize DP23211 does not represent a nutritional concern in humans and animals. Therefore, no post-market monitoring of food/feed is considered necessary. In the case of accidental release of viable maize DP23211 grains into the environment, this would not raise environmental safety concerns. The post-market environmental monitoring plan and reporting intervals are in line with the intended uses of maize DP23211. The GMO Panel concludes that maize DP23211 is as safe as its conventional counterpart and the tested non-GM reference varieties with respect to potential effects on human and animal health and the environment.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10794937PMC
http://dx.doi.org/10.2903/j.efsa.2024.8483DOI Listing

Publication Analysis

Top Keywords

maize dp23211
36
maize
9
dp23211
9
genetically modified
8
modified maize
8
food feed
8
conventional counterpart
8
gmo panel
8
safety concerns
8
safety
5

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!