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Gabapentin and pregabalin, which belong to the gabapentinoid drug family, are widely used, especially in neuropathic pain treatment, due to their effectiveness in pain management. Although many of the comorbidities and symptoms that limit the use of gabapentinoids are clearly described in the literature, there is limited data on their use during lactation. A 33-year-old female patient was admitted to our clinic with neuropathic pain and muscle weakness in her left lower extremity following spinal anesthesia for a cesarean section. We aimed to present the gabapentin treatment of a breastfeeding patient with persistent neuropathic pain in light of a literature review.
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http://dx.doi.org/10.14744/agri.2021.55531 | DOI Listing |
Neuropsychopharmacology
March 2025
NMPA Key Laboratory for Research and Evaluation of Narcotic and Psychotropic Drugs, Xuzhou, China.
Neuropathic pain, which has become a major public health concern, is frequently accompanied by the deterioration of affective behavior and cognitive function. However, the brain circuitry underlying these changes is poorly understood. Therefore, we aimed to identify in a mouse model the converging circuit that influences the sensory, affective, and cognitive consequences of neuropathic pain.
View Article and Find Full Text PDFBr J Anaesth
March 2025
Division of Clinical Psychology and Psychological Intervention, Institute of Psychology, University of Duisburg-Essen, Essen, Germany.
Chronic postsurgical pain (CPSP) is associated with reduced health-related quality of life and disability. In some patients, it can result in long-term opioid use even after minor surgery. Epidemiological studies have reported highly varying rates of CPSP, largely because researchers have used different definitions with self-defined cut-offs for pain scores.
View Article and Find Full Text PDFPhytomedicine
March 2025
Jiangsu Key Laboratory of TCM Evaluation and Translational Research, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu 211198, China. Electronic address:
Background: The pathologic mechanism of neuropathic pain (NP) is still not fully understood, and efficient and safe therapeutic options are limited.
Purpose: Seeking new treatment options for neuropathic pain.
Study Design: Exploring new therapeutic target for NP and finding analgesic medications derived from traditional Chinese medicines against the target is urgent.
PM R
March 2025
Department of Pain Medicine, Mayo Clinic, Jacksonville, Florida, USA.
Metabolic syndrome (MetS) is a prevalent comorbidity in patients with chronic pain conditions. Emerging evidence suggests that the relationship between MetS and chronic pain is bidirectional. This interplay involves complex mechanisms, including proinflammatory mediators in nociceptive modulation and pain-induced lifestyle changes affecting metabolic function.
View Article and Find Full Text PDFSci Rep
March 2025
Department of Neurosurgery, The Spine and Spinal Cord Institute, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul, 06273, Republic of Korea.
This article aimed to assess the efficacy of surgical treatments, particularly arthrodesis with C2 nerve transection, in patients with atlantoaxial osteoarthritis (AAOA). Data of patients with AAOA who underwent surgical treatment between January 2020 and November 2023 were retrospectively collected. Of 11 patients with AAOA, nine underwent fusion surgery, and two underwent decompression surgery.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!