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| http://dx.doi.org/10.1038/s41408-024-00984-1 | DOI Listing |
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Mental health risks in pregnancy and early parenthood among male and female parents following unintended pregnancy or fertility treatment: a cross-sectional observational study.
BMC Pregnancy Childbirth
December 2024
Department of Legal Medicine, Toho University School of Medicine, Tokyo, Japan.
Article Synopsis
- Unintended pregnancies are associated with increased mental health risks, particularly for women, who experience higher levels of psychological distress, chronic pain, and death fantasies compared to those with intended pregnancies.
- The study analyzed responses from over 7,000 women and 1,700 men, examining various conception methods and their impact on mental health before and after childbirth.
- Additionally, men undergoing fertility treatments, especially those using scheduled intercourse or insemination, also exhibited significant mental health challenges, highlighting the need for support in these populations.
Parenthood in a Swedish prospective cohort of 1,378 adolescents and young adults banking semen for fertility preservation at time of cancer diagnosis.
Front Endocrinol (Lausanne)
December 2024
Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Background: The possibility of future parenthood is a highly relevant issue for patients of reproductive age facing oncologic treatment. This study aimed to investigate how fatherhood was achieved in a patient cohort of adolescents and young adults (AYAs) banking semen at time of cancer diagnosis and to determine the effectiveness of cryopreservation aimed at fertility preservation in the cohort.
Materials And Methods: Observational cohort study examining AYAs with a cancer diagnosis who underwent semen banking for fertility preservation at Karolinska University Hospital 1988-2020, as part of the Stockholm regional fertility preservation program.
Spinal muscular atrophy is also a disorder of spermatogenesis.
Orphanet J Rare Dis
December 2024
Centre de Référence Des Maladies Neuromusculaires AOC, CHU de Nantes, Filnemus, Euro-NMD, Hôtel Dieu, Nantes, France.
Background: Spinal muscular atrophy (SMA) patients benefit from pre-mRNA splicing modifiers targeting the SMN2 gene, which aims to increase functional SMN production. The animal toxicity affecting spermatogenesis associated with one such treatment raised questions about male SMA patients' spermatogenesis.
Methods: This descriptive, cross-sectional study was conducted from June 2022 to July 2023.
Over the last 15 years, many European countries have experienced fertility declines. Existing research on this shift in fertility behavior points to economic aspects and increased levels of uncertainty as important drivers. However, in this debate little attention has been paid to how the relevance of individual- and contextual-level dimensions for understanding the new fertility patterns varies by level of urbanization.
View Article and Find Full Text PDFReproductive functions and fertility preservation in transgender men: A French case series.
J Gynecol Obstet Hum Reprod
December 2024
Service de Biologie de la Reproduction CECOS, Hôpital Tenon (AP-HP), Sorbonne-Université 75020 PARIS, France; Sorbonne Université, Centre de recherche Saint-Antoine, Inserm US938 75012 PARIS, France. Electronic address:
Background: Transgender men face reproductive challenges due to the potential impact on fertility of gender-affirming hormone therapy (GAHT) and surgical interventions. Testosterone therapy during "female to male" transition leads to anovulation and amenorrhea. Although these effects are typically reversible upon stopping treatment, the long-term effects of androgens on future fertility and health of potential children remain poorly known.
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