Attenuation of cell-free DNA clearance in vivo is an alternative strategy to maximize recovery.
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http://dx.doi.org/10.1126/science.adn1886 | DOI Listing |
A crucial component of the high-contrast instrumental chain in astronomy is the wavefront sensor (WFS). A key property of this component is its sensitivities, which reflect its ability to efficiently use incoming photons to encode the phase aberrations. This paper introduces a new class of highly sensitive wavefront sensors that approach the fundamental sensitivity limits dictated by physics.
View Article and Find Full Text PDFSci Rep
January 2025
School of Computer Science and Technology, Donghua University, Shanghai, 201620, China.
Extracting high-order abstract patterns from complex high-dimensional data forms the foundation of human cognitive abilities. Abstract visual reasoning involves identifying abstract patterns embedded within composite images, considered a core competency of machine intelligence. Traditional neuro-symbolic methods often infer unknown objects through data fitting, without fully exploring the abstract patterns within composite images and the sequential sensitivity of visual sequences.
View Article and Find Full Text PDFTransl Oncol
January 2025
Northern Jiangsu People's Hospital Affiliated to Yangzhou University, China; Department of Hepatobiliary Surgery, Northern Jiangsu People's Hospital, China. Electronic address:
Sorafenib and lenvatinib are frontline treatments for advanced hepatocellular carcinoma (HCC). While lenvatinib surpasses sorafenib in efficacy and tolerability, resistance remains a significant clinical challenge. Recent research highlights the potential of TRIM family proteins in modulating lenvatinib resistance in HCC, necessitating a deeper understanding of their specific mechanisms.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Radiology, Yantaishan Hospital, Yantai, Shandong, China.
Diabetic retinopathy, a retinal disorder resulting from diabetes mellitus, is a prominent cause of visual degradation and loss among the global population. Therefore, the identification and classification of diabetic retinopathy are of utmost importance in the clinical diagnosis and therapy. Currently, these duties are extensively carried out by manual examination utilizing the human visual system.
View Article and Find Full Text PDFPurpose: We hypothesised that applying radiomics to [F]PSMA-1007 PET/CT images could help distinguish Unspecific Bone Uptakes (UBUs) from bone metastases in prostate cancer (PCa) patients. We compared the performance of radiomic features to human visual interpretation.
Materials And Methods: We retrospectively analysed 102 hormone-sensitive PCa patients who underwent [F]PSMA-1007 PET/CT and exhibited at least one focal bone uptake with known clinical follow-up (reference standard).
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