AI Article Synopsis
- Intravital microscopy enables real-time observation of cell behavior within a living organism's complex environment.
- This technique allows for longitudinal studies, tracking structural and functional changes over extended periods in the same animal.
- In cancer research, the dorsal window chamber model is preferred for studying tumor-related processes like cell migration and interactions between cells and blood vessels, using advanced microscopy methods for detailed analysis.
Article Abstract
Intravital microscopy allows a direct visualization of cells' behavior in their environment in a living organism with all its complexity. With appropriated models, longitudinal studies of structural and functional changes can be followed in the same animal on long period. In the field of cancer, the dorsal window chamber model is the model of choice for tumor events such as cells migration, vessels growth, and their permeability or interactions between cells and vessels. Coupled with wide-field, confocal, or multiphoton fluorescence microscopes, high spatial and temporal resolutions of the cellular events can be analyzed in vivo.
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| http://dx.doi.org/10.1007/978-1-0716-3714-2_12 | DOI Listing |
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