Background: Neonates with critical congenital heart defects (CCHD neonates) experience high rates of feeding intolerance, necrotizing enterocolitis (NEC), and malnutrition. The benefits of human milk and direct chest/breastfeeding are well known, but research is limited in CCHD neonates. Therefore, the purpose of this study is to examine the impact of neonatal diet and feeding modality on the incidence of feeding intolerance, NEC, and malnutrition among a cohort of CCHD neonates.
Methods: A single-center retrospective study was conducted using electronic health record data of CCHD neonates admitted to a cardiac intensive care unit between April 2016 and April 2020. Regression models were fit to analyze associations between neonatal diet, feed modality, and adverse feeding outcomes.
Results: Seventy-four CCHD neonates were included. Increased days of direct chest/breastfeeding were associated with fewer signs of gastrointestinal distress ( P = .047) and bloody stools ( P = .021). Enteral feeding days of "all human milk" were associated with higher growth trajectory ( P < .001).
Conclusions: Human milk and direct chest/breastfeeding may be protective against some adverse feeding outcomes for CCHD neonates. Larger, multicenter cohort studies are needed to continue investigating the effects of neonatal diet type and feeding modality on the development of adverse feeding outcomes in this unique population.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10807746 | PMC |
| http://dx.doi.org/10.1097/JPN.0000000000000790 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Utilization of Acetaminophen for Managing PGE1-Induced Fever in Neonates with Critical Congenital Heart Disease.
Children (Basel)
December 2024
Department of Neonatology, SBU. Dr. Sami Ulus Maternity and Child Research and Training Hospital, Babur St., Number: 36, Altındag 06080, Turkey.
Introduction: We aimed to retrospectively evaluate the use of acetaminophen, which may be a risk factor for the ductal canal, in the treatment of fever due to prostaglandin E1 (PGE1) infusion in newborns with critical congenital heart disease (CCHD).
Methods: The study included newborns who were followed-up in our neonatal intensive care unit with the diagnosis of critical congenital heart disease, developed fever due to PGE1 infusion and had acetaminophen administered for antipyretic treatment. The patent ductus arteriosus diameters of the patients were evaluated by echocardiographic imaging before intravenous acetaminophen treatment and at the end of the day of acetaminophen treatment.
Prevalence and Patterns of Antibiotic Administration in Neonates With Critical Congenital Heart Defects.
J Perinat Neonatal Nurs
December 2024
Author Affiliations: Department of Pediatrics, Division of General Academic Pediatrics (Davis and Martin), UMPC Children's Hospital of Pittsburgh (Davis, Seiler, Ghassemzadeh, Firek, Quigley, Kreutzer, Morowitz), Department of Critical Care Medicine (Ghassemzadeh, Baust, Quigley), Department of Pediatrics, Division of Cardiology (Kreutzer); Department of Health and Community Systems (Ren), and Department of Surgery (Morowitz), University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Background: Although data exists demonstrating widespread antibiotic use across other critically ill neonatal populations, there are limited data regarding the frequency of empiric antibiotic use among neonates with critical congenital heart defects (CCHD). The purpose of this study is to describe prevalence of antibiotic treatment in the first 28 days of life in a cohort of neonates with CCHDs.
Methods: A secondary analysis of retrospective electronic health record data of neonates admitted to a Pennsylvania pediatric hospital for cardiac surgery (2016-2020).
Newborn Screening for Critical Congenital Heart Disease: A New Algorithm and Other Updated Recommendations: Clinical Report.
Pediatrics
January 2025
Children's National Hospital, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia.
Critical congenital heart disease (CCHD) screening was added to the US Recommended Uniform Screening Panel in 2011 and adopted by all US states and territories by 2018. In addition to reviewing key developments in CCHD screening since the initial American Academy of Pediatrics (AAP) endorsement in 2011, this clinical report provides 3 updated recommendations. First, a new AAP algorithm has been endorsed for use in CCHD screening.
View Article and Find Full Text PDFPreoperative autonomic failure in neonates with critical congenital heart disease.
Early Hum Dev
January 2025
The Zickler Family Prenatal Pediatrics Institute, Children's National Hospital, Washington, DC, USA; The Developing Brain Institute, Children's National Hospital, Washington, DC, USA; Department of Pediatrics, The George Washington University School of Medicine, Washington, DC, USA. Electronic address:
Background: Neonates with critical congenital heart disease (cCHD) undergo a complicated transition to ex-utero life. However, continuous monitoring of autonomic tone using heart rate variability is currently lacking.
Materials And Methods: We retrieved continuous electrocardiograms from the time of admission or from 10 days prior to surgery for neonates with dextro-transposition of the great arteries (d-TGA) and hypoplastic left heart syndrome (HLHS).
A novel simulation to prepare maternal caregivers of children diagnosed with a critical congenital heart defect.
J Pediatr Nurs
November 2024
Wellstar School of Nursing, Kennesaw State University, Kennesaw, Georgia.
Purpose: The purpose of this feasibility study was to determine the effectiveness of an interprofessional led low-fidelity simulation program over three timepoints on maternal caregivers' perceived stress, sense of competence and discharge readiness for care of critical congenital heart disease (CCHD) infants requiring neonatal cardiac surgery.
Design And Methods: The Perceived Stress Scale (PSS) was administered to simulation and non-intervention groups at three timepoints: prenatal period, Cardiac Acute Care Unit (CACU) transfer, and rooming-in. Parental Sense of Competence (PSOC) was measured at timepoint two and three, and Readiness for Hospital Discharge (RDHS) was measured at timepoint three for the simulation group.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!