High-performance magnetic metal microrobot prepared by a two-photon polymerization and sintering method.

Lab Chip

CAS Key Laboratory of Mechanical Behavior and Design of Materials, Key Laboratory of Precision Scientific Instrumentation of Anhui Higher Education Institutes, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei 230027, China.

Published: February 2024

AI Article Synopsis

  • Magnetically-actuated microrobots (MARs) are promising for biomedicine due to their precise navigation and remote operation, but many suffer from low magnetic content, limiting their effectiveness.
  • A new high-performance pure-nickel microrobot (Ni-MAR) was developed, featuring about 90% magnetic content, leading to improved magnetic torque and allowing for faster speeds and better cargo carrying capabilities.
  • The Ni-MAR can swim at a maximum velocity of 12.5 body lengths per second, carry a load 200 times its weight, and effectively transport single or multiple cells, making it a strong candidate for targeted therapies and drug delivery.

Article Abstract

Magnetically-actuated microrobots (MARs) exhibit great potential in biomedicine owing to their precise navigation, wireless actuation and remote operation in confined space. However, most previously explored MARs unfold the drawback of hypodynamic magnetic torque due to low magnetic content, leading to their limited applications in controlled locomotion in fast-flowing fluid and massive cargo carrying to the target position. Here, we report a high-performance pure-nickel magnetically-actuated microrobot (Ni-MAR), prepared by a femtosecond laser polymerization followed by sintering method. Our Ni-MAR possesses a high magnetic content (∼90 wt%), thus resulting in enhanced magnetic torque under low-strength rotating magnetic fields, which enables the microrobot to exhibit high-speed swimming and superior cargo carrying. The maximum velocity of our Ni-MAR, 12.5 body lengths per second, outperforms the velocity of traditional helical MARs. The high-speed Ni-MAR is capable of maintaining controlled locomotion in fast-flowing fluid. Moreover, the Ni-MAR with massive cargo carrying capability can push a 200-times heavier microcube with translation and rotation motion. A single cell and multiple cells can be transported facilely by a single Ni-MAR to the target position. This work provides a scheme for fabricating high-performance magnetic microrobots, which holds great promise for targeted therapy and drug delivery .

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Source
http://dx.doi.org/10.1039/d3lc01084hDOI Listing

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