A convenient method has been developed for transforming alkyl halides into the corresponding alcohols an S2 reaction. Treatment of an alkyl halide with the squarate dianion at high temperature produces mono-alkyl squarate, and a one-pot basic hydrolysis of the intermediate affords the alcohol in good yield.

Download full-text PDF

Source
http://dx.doi.org/10.1039/d3ob01507fDOI Listing

Publication Analysis

Top Keywords

alkyl halides
8
squarate dianion
8
alcohol synthesis
4
synthesis based
4
based reactions
4
reactions alkyl
4
halides squarate
4
dianion convenient
4
convenient method
4
method developed
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!