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Burden of employment loss and absenteeism in adults and caregivers of children with sickle cell disease. | LitMetric

AI Article Synopsis

  • Sickle cell disease (SCD) affects around 100,000 people in the U.S. and costs about $3 billion for medical care each year, but the financial struggles of patients are not well understood.
  • A study surveyed patients and caregivers to see how SCD affects their jobs and work attendance, finding many people miss work or lose their jobs because of the disease.
  • The findings show that adults with SCD and caregivers often deal with job loss and missing workdays, which adds up to a serious economic burden that should be considered in future health evaluations.

Article Abstract

Sickle cell disease (SCD) is a genetic disorder affecting 100 000 people with an estimated annual medical cost of $3 billion in the United States; however, the economic impact on patients is not well described. We aimed to examine the indirect economic burden and test the hypothesis that socioeconomic status and greater social vulnerability risks are associated with increased absenteeism and employment loss. We surveyed adults and caregivers of children with SCD at 5 US centers from 2014 to 2021. Logistic regression models were used to examine the associations of employment loss and missed days of work with demographics and social determinants. Indirect costs were estimated by multiplying the self-reported missed days of work and job loss by 2022 average wages by the state of the participating institution. Of the 244 participants, 10.3% reported employment loss in the last 5 years, and 17.5% reported missing 10 or more days of work. Adults had 3 times more employment loss compared with caregivers of children with SCD (OR, 3.18; 95% CI, 1.12-9.01) but fewer missed days of work (OR, 0.24; 95% CI, 0.11-0.0.51). Participants who did not live with a partner reported increased employment loss (OR, 4.70; 95% CI, 1.04-21.17) and more missed days of work (OR, 4.58; 95% CI, 1.04-20.15). The estimated annual indirect economic burden was $2 266 873 ($9290 per participant). Adults with SCD and caregivers of children with SCD commonly report employment loss and missed days of work as important risk factors. The high indirect economic burden suggests that future economic evaluations of SCD should include SCD-related indirect economic burden.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10909714PMC
http://dx.doi.org/10.1182/bloodadvances.2023012002DOI Listing

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