Background: Common etiologies of sciatic mononeuropathy are compressive, infiltrative, traumatic, or diabetic. However, in a proportion of patients, the etiology remains elusive despite extensive serological, electrophysiological, radiological, and histological investigations.
Methods: Patients with unexplained sciatic mononeuropathy were studied with regard to their clinical, radiological, pathological, and treatment aspects.
Results: We could identify five cases of sciatic mononeuropathy wherein the etiology remained unknown even after a comprehensive evaluation. The compressive, metabolic, hematological, and immune causes were ruled out with necessary investigations. The clinical, electrophysiological, radiological, and histological features of these patients are discussed.
Conclusion: The etiology of sciatic mononeuropathy can remain obscure in certain instances in spite of the comprehensive workup. The role of investigations and the exclusion process of various diagnostic entities are discussed.
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http://dx.doi.org/10.4103/aian.aian_566_23 | DOI Listing |
Rev Bras Ortop (Sao Paulo)
November 2024
Instituto Vita, São Paulo, São Paulo, Brasil.
Common fibular nerve (CFN) palsy is the most common mononeuropathy in the lower limb, and several etiologies are described. The CFN is the minor and lateral division of the sciatic nerve; it originates in the lumbar sacral division, and many risks of compression have been described: the behavior of crossing and squatting legs, extra and intraneural compressions, local trauma, and weight loss have been increasingly reported as important and noteworthy causes. The treatment is based on the severity of the nerve condition.
View Article and Find Full Text PDFBMC Musculoskelet Disord
December 2024
Department of Orthopaedics Surgery, Shandong Provincial Hospital affiliated to Shandong First Medical University, Jinan, People's Republic of China.
Purpose: Floating hip is a severe high-energy injury. Femoral fracture is an essential component of floating hip. However, few studies have addressed the relationship between the femoral fracture pattern and floating hip injury.
View Article and Find Full Text PDFBMC Neurosci
November 2024
Department of Orthopedics, The Affiliated Hospital, Southwest Medical University, Luzhou, 646099, China.
Objective: Observing the effects of Tetramethylpyrazine (TMP) on the expression of Collagen IV and Laminin in neurovascular basement membrane and the apoptosis of vascular endothelial cells, and to study the mechanism of TMP in the treatment of sciatic nerve injury.
Results: Compared with the NS group, the TMP group had a significant increase in the sciatic nerve function index (P < 0.01).
Turk Neurosurg
November 2024
Bursa Uludag University Faculty of Medicine, Department of Neurosurgery, Bursa, Türkiye.
Aim: To investigate the possible mediation of epigenetic mechanisms underlying the regenerative effect of uridine in a sciatic nerve transection rat model.
Material And Methods: Fifty adult male rats were randomized to sham, control, and uridine groups. After unilateral transection and primary anastomosis of the right sciatic nerve, a single daily dose of saline (1 ml/kg; sham and control groups) or uridine (500 mg/kg; uridine group) was injected intraperitoneally for a week.
Mymensingh Med J
October 2024
Dr Rezwanul Karim Shams, Clinical Assistant, General Surgery, United Hospital Ltd. Bangladesh; E-mail:
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