Background: Surgical treatment remains the mainstream therapeutic regimen for chronic subdural hematoma (CSDH), and burr-hole craniostomy with subdural drainage is the preferable approach. Herein, we reported a case of intracranial granuloma formation as a late complication of burr-hole surgery for CSDH.
Case Presentation: A 31-year-old man presented with a 1-month history of headache. Head computed tomography (CT) showed a subdural hematoma in the left frontal-temporal-parietal region with significant midline shifting. A burr-hole evacuation of the hematoma with closed-system drainage was performed. CT obtained immediately after the surgery demonstrated that the hematoma was mostly evacuated. Nine months later, he presented to us again due to intermittent headache in the left temporoparietal region. Brain magnetic resonance imaging revealed a space-occupying mass at the site of the original hematoma. A bone-flap craniotomy was performed for resecting the mass. Histopathological examination revealed a granuloma. The microbial cultivation of the resected specimen was negative. The postoperative course was uneventful, and the headache was relieved.
Conclusion: Granuloma formation is an extremely rare late complication of burr-hole surgery for CSDH. Physicians involved in the perioperative management of CSDH should be aware of this condition, and bone-flap craniotomy may be warranted.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1080/02699052.2024.2304860 | DOI Listing |
Int J Mol Sci
December 2024
Anatomy and Physiopathology Division, Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.
Respiratory infections, including tuberculosis, constitute a major global health challenge. Tuberculosis (TB), caused by (Mtb), remains one of the leading causes of mortality worldwide. The disease's complexity is attributed to Mtb's capacity to persist in latent states, evade host immune defenses, and develop resistance to antimicrobial treatments, posing significant challenges for diagnosis and therapy.
View Article and Find Full Text PDFActa Parasitol
January 2025
Federal University of São João del-Rei, Divinópolis, MG, Brazil.
Purpose: Schistosomiasis remains a parasitic disease affecting millions of people worldwide, requiring interventions like vaccination. In previous work, our group used reverse vaccinology to identify two epitopes from the Schistosoma mansoni proteins, Sm050890 (44-58) and Sm141290 (225-239). This study evaluated the immune response profile and protection induced by peptides, as a mixture of immunogens, in murine vaccination trials.
View Article and Find Full Text PDFCase Rep Infect Dis
December 2024
Department of Dermatology, North Bristol NHS Trust, Bristol, UK.
was first described in humans in 1954, known to infect fish species and contaminate water and fish products. Inoculation to humans occurs through injured skin resulting in the formation of a solitary nodule known as "fish tank granuloma." Disseminated infections have been reported in the immunocompromised and can present with extracutaneous manifestations such as arthritis and osteomyelitis.
View Article and Find Full Text PDFHum Immunol
December 2024
Department of Rheumatology, Faculty of Medicine, Firat University, Elazig, Turkey.
Background: Idiopathic granulomatous mastitis (IGM) is a chronic inflammatory disorder characterised by the formation of non-caseating granulomas in breast tissue, primarily affecting young women of childbearing age. The aetiology of IGM remains unclear, with potential factors including trauma, hormonal influences, and autoimmune responses. Recent studies suggest that immune dysregulation may play a critical role in IGM, highlighting the need for exploration of biomarkers involved in inflammation and immune modulation, particularly LL-37, galectin-3, IL-36, and TLR3.
View Article and Find Full Text PDFCureus
November 2024
Ophthalmology/Oculoplasty, Hospital Serdang, Kajang, MYS.
Objective: This study aims to determine the outcomes of probing and external dacryocystorhinostomy (exDCR) for congenital nasolacrimal duct obstruction (cNLDO) and the factors influencing the success rates in pediatric cNLDO.
Design: A retrospective sample collection was conducted at the oculoplastic referral center over 10 years (January 2012 to December 2022) for cNLDO patients who had undergone probing or exDCR.
Methodology: Data were retrospectively reviewed for patients aged ≤18 years who underwent probing or exDCR.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!