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| http://dx.doi.org/10.1186/s12969-024-00956-6 | DOI Listing |
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The Fat-Dachsous planar polarity pathway competes with hinge contraction to orient polarized cell behaviors during Drosophila wing morphogenesis.
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School of Biosciences, University of Sheffield, Firth Court, Sheffield, S10 2TN, UK. Electronic address:
During tissue morphogenesis, an interplay of biochemical pathways and mechanical cues regulates polarized cell behaviors, the balance of which leads to tissues reaching their correct shape and size. A well-studied example of a biochemical regulator is the highly conserved Fat-Dachsous (Ft-Ds) pathway that coordinates planar polarized cell behaviors and growth in epithelial tissues. For instance, in the Drosophila larval wing disc, the Ft-Ds pathway acts via the atypical myosin Dachs to control tissue shape by promoting the orientation of cell divisions primarily in a proximodistal (PD) direction.
View Article and Find Full Text PDFTarget trial emulation to evaluate the effect of immune-related adverse events on outcomes in metastatic urothelial cancer.
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Department of Surgical Oncology (Urology), Netherlands Cancer Institute, Amsterdam, The Netherlands.
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Department of Burns and Plastic Surgery, University Hospital Brno, Jihlavska 20, Brno, 62500, Czech Republic.
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View Article and Find Full Text PDFThe Rhode Island transitions clinic: connections to social and healthcare services after release from incarceration.
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View Article and Find Full Text PDFThe influence of orthodontist change on treatment duration and outcomes in patients treated with Clark's twin block appliance followed by non-extraction fixed mechanotherapy - a retrospective cohort study.
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