AI Article Synopsis
- Aphasic status epilepticus (ASE) is a type of seizure where aphasia, a language disorder, is the only symptom, and Alzheimer's disease (AD) can lead to this condition.
- The cases of two patients with ASE due to AD showed different types of aphasia (Broca's and global) and unusual EEG patterns that improved with antiepileptic medication.
- Recognizing the changes in symptoms and EEG after treatment is essential for diagnosing ASE, and timely intervention is crucial to avoid further impairment of consciousness in patients with AD.
Article Abstract
In aphasic status epilepticus (ASE), aphasia is the sole manifestation of seizure in patients with this disorder. Alzheimer's disease (AD) is one of neurological disorders causing ASE. Herein, we report two cases of ASE associated with AD, and discuss their clinical characteristics. Patient 1 presented Broca's aphasia, and patient 2 presented global aphasia during the ictal period. Both patients exhibited atypical ictal electroencephalographic (EEG) patterns, which improved after antiepileptic drug administration. ASE was the presenting symptom of AD in patient 1. ASE can develop at any stage of AD. Alterations in clinical symptoms and EEG patterns after treatment with antiepileptic drug are the key to diagnosis. Prompt diagnosis and treatment are critical for preventing further consciousness dysfunction.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10783961 | PMC |
| http://dx.doi.org/10.14581/jer.23009 | DOI Listing |
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