Countless decisions and actions in daily life draw on a mental model of the physical structure and dynamics of the world - from stepping carefully around a patch of slippery pavement to stacking delicate produce in a shopping basket. People can make fast and accurate inferences about how physical interactions will unfold, but it remains unclear whether we do so by applying a general set of physical principles across scenarios, or instead by reasoning about the physics of individual scenarios in an ad-hoc fashion. Here, we hypothesized that humans possess a dedicated and flexible mental resource for physical inference, and we tested for such a resource using a battery of fine-tuned tasks to capture individual differences in performance. Despite varying scene contents across tasks, we found that performance was highly correlated among them and well-explained by a unitary intuitive physics resource, distinct from other facets of cognition such as spatial reasoning and working memory.
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http://dx.doi.org/10.1016/j.isci.2023.108607 | DOI Listing |
Nutrients
January 2025
Department of Nutrition Science, Purdue University, West Lafayette, IN 47907, USA.
Background/objectives: The study's objective was to determine whether social isolation serves as a mediator in the cross-sectional relationship between food insecurity, both as a short-term and longer-term situation, with resource use and depressive symptoms as outcomes.
Methods: This cross-sectional design study utilized secondary survey data, including 30-day and 12-month food security measured by the U.S.
J Clin Med
January 2025
Young Leaders Advocacy Group, Diabetes Research Institute Foundation, Hollywood, FL 33021, USA.
Type 1 Diabetes (T1D) is a progressive autoimmune disease often identified in childhood or adolescence, with early stages detectable through pre-diabetic markers such as autoantibodies and subclinical beta-cell dysfunction. The identification of the pre-T1D stage is critical for preventing complications, such as diabetic ketoacidosis, and for enabling timely interventions that may alter disease progression. This review examines the multifaceted approach to managing T1D risk in adolescents and teens, emphasizing early detection, nutritional interventions, beta-cell preservation strategies, and psychosocial support.
View Article and Find Full Text PDFJ Clin Med
January 2025
Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh 11149, Saudi Arabia.
Mental health issues can significantly affect the health-related quality of life (HRQoL) of adults suffering from hyperlipidemia. Therefore, in this study, the aim was to examine how depression and anxiety are related to the HRQoL of adults with hyperlipidemia. Data from the Medical Expenditure Panel Survey for 2016 through 2022 were used to identify adult patients diagnosed with hyperlipidemia aged 18 or older.
View Article and Find Full Text PDFBiomolecules
January 2025
Research and Education Resource Center, Peoples Friendship University of Russia (RUDN University), 117198 Moscow, Russia.
Post-translational modifications of proteins via palmitoylation, a thioester linkage of a 16-carbon fatty acid to a cysteine residue, reversibly increases their affinity for cholesterol-rich lipid rafts in membranes, changing their function. Little is known about how altered palmitoylation affects function at the systemic level and contributes to CNS pathology. However, recent studies suggested a role for the downregulation of palmitoyl acetyltransferase (DHHC) 21 gene expression in the development of Major Depressive Disorder (MDD)-like syndrome.
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