AI Article Synopsis
- * AFE incidence was consistent at about 4.9 cases per 100,000 deliveries, while the case-fatality rate showed a decline to an average of 17.7%.
- * Higher AFE rates and fatalities were observed in women aged 35 and older, African-Americans, and those in urban-teaching hospitals, indicating a need for further research on diagnosis and treatment strategies.
Article Abstract
Objective: To estimate incidence and case-fatality rates of amniotic fluid embolism (AFE) and to examine their temporal trends.
Study Design: Population-based retrospective cohort study using the 2000-2019 Health Care Cost and Utilization Project, Nationwide Inpatient Sample (HCUP-NIS). Annual population rates were estimated using HCUP-NIS specific weighting. Descriptive analyses and logistic regression described trends within the cohort.
Results: Over the study period, AFE incidence rate remained stable (mean 4.9 cases/100,000 deliveries) and the case-fatality rate declined (mean 17.7 %,95 % CI 16.40-10.09). Highest AFE incidence rates and fatality rates were in women ≥ 35 years, African-Americans, and in urban-teaching hospitals. AFE mortality rates decreased among Hispanics.
Conclusion: AFE rates remained stable and fatality rates declined over time. Highest rates of AFE occurrence and death were in women who typically have greater risk of experiencing adverse obstetrical outcomes. Continued research into early diagnostic methods and effective treatments are needed to further improve AFE incidence and mortality rates.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ejogrb.2023.12.034 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug-drug interactions.
CPT Pharmacometrics Syst Pharmacol
December 2024
Department of Epidemiology and Biostatistics, School Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Topiramate (TPM) is a broad-spectrum antiepileptic drug (AED) commonly prescribed for approved and off-label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
View Article and Find Full Text PDFPancreatic cancer risk after benign gallbladder disease: A Swedish population-based cohort study.
Eur J Cancer
January 2025
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; General Practice Research Unit (AFE) and Department of General Practice, Institute of Health and Society, University of Oslo, Oslo, Norway; Vårdcentralen Värmlands Nysäter and Centre for Clinical Research, County Council of Värmland, Värmland, Sweden.
Article Synopsis
- - The study aimed to investigate the risk of pancreatic cancer following benign gallbladder disease (GBD) in a nationwide cohort of Swedish individuals aged 20-79 who had undergone cholecystitis or cholecystectomy from 1992 to 2016, along with matched non-exposed individuals.
- - Over a 15-year period, the researchers found that those with a history of GBD had a significantly higher incidence of pancreatic cancer within the first two years after diagnosis, with a hazard ratio of 2.74, particularly in younger patients aged 20-49, where the risk was even more pronounced.
- - The results suggest the need for increased clinical monitoring for pancreatic cancer in patients who have
Assessment of knowledge and attitude of healthcare professionals towards Mpox in a Nigerian hospital.
Sci Rep
November 2024
Department of Public Health, College of Medicine and Health Sciences, Afe Babalola University, Ado- Ekiti, Ekiti state, Nigeria.
Mpox is a zoonotic viral disease that presents significant public health challenges. Despite the pivotal role of healthcare workers, research on their knowledge and attitudes towards mpox is limited. This study aimed to assess healthcare workers' knowledge, awareness and attitude regarding mpox as well as associated factors at Rivers State University Teaching Hospital in Nigeria.
View Article and Find Full Text PDFExamination of plasma biomarkers of amyloid, tau, neurodegeneration, and neuroinflammation in former elite American football players.
Alzheimers Dement
November 2024
Boston University CTE Center, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.
Article Synopsis
- - Blood-based biomarkers are being explored to detect brain injuries from repetitive head impacts, specifically in former football players, by analyzing plasma levels of various proteins like tau and amyloid.
- - A study involving 180 former football players and 60 control participants found that specific biomarkers (p-tau181 and p-tau231) were significantly elevated in the football players, indicating potential brain damage linked to their sport.
- - The findings suggest that certain plasma proteins (p-tau, GFAP, NfL) could help in understanding and identifying neurological issues related to head impacts, with younger players showing more severe biomarker changes.
Understanding the roles of Alternative Rites of Passage and Public Declarations in FGM/C abandonment: An ethnographic study among the Loita Maasai, Kenya.
Soc Sci Med
October 2024
University of Nairobi, Kenya. Electronic address:
Article Synopsis
- This article talks about how the Maasai community in Kenya is changing their views on Female Genital Mutilation/Cutting (FGM/C) and what's helping that change.
- Researchers found that a group called S.A.F.E. is helping by creating songs and a new way to celebrate girls’ initiation that doesn't involve FGM/C.
- Although some people in the community still practice FGM/C due to cultural beliefs, changes in education and laws are slowly making it less common.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!