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HSV-associated chronic granulomatous encephalitis in a child.
J Neuropathol Exp Neurol
February 2024
Department of Laboratory Medicine and Pathology, Wake Forest University School of Medicine, Atrium Health Wake Forest Baptist Hospital, Winston Salem, North Carolina, USA.
HSV-associated erythema multiforme in a patient after hematopoietic stem cell transplantation.
Dermatol Ther
September 2019
Peking University People's Hospital, Beijing, China.
Herpes simplex virus (HSV)-associated erythema multiforme (HAEM) is an acute and self-limiting mucocutaneous hypersensitivity reaction triggered by herpes virus infections. We reported a patient with HAEM after hematopoietic stem cell transplantation (HSCT). A 55-year-old man received HSCT 7 months ago.
View Article and Find Full Text PDFBiologic interactions between HSV-2 and HIV-1 and possible implications for HSV vaccine development.
Vaccine
November 2019
World Health Organization, Department of Reproductive Health and Research, Geneva, Switzerland.
Development of a safe and effective vaccine against herpes simplex virus type 2 (HSV-2) has the potential to limit the global burden of HSV-2 infection and disease, including genital ulcer disease and neonatal herpes, and is a global sexual and reproductive health priority. Another important potential benefit of an HSV-2 vaccine would be to decrease HIV infections, as HSV-2 increases the risk of HIV-1 acquisition several-fold. Acute and chronic HSV-2 infection creates ulcerations and draws dendritic cells and activated CD4+ T cells into genital mucosa.
View Article and Find Full Text PDFImmunologic Profile of Patients Suffering from Herpes Simplex Virus (HSV) -Associated Oral Lesions Treated with Natural Human Interferon Alpha (Egiferon).
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January 1997
Semmelweis University of Medicine, Department of Maxillofacial Surgery, Budapest, Hungary.
10 consecutive patients with HSV-associated chronic oral lesions were treated with Egiferon for ten days. There were a statistically significant increase in the Large Granule Lymphocyte (LGL) counts and the number of spontaneous E rosette forming cells by the end of the treatment period. Interferon alpha brought about a preferential expression of CD8, CD11b, CD14, CD25 and CD45RO cell surface molecules without any effect on the expression of CD2, CD3, CD4, CD20 and HLA-DR.
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