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Focal Fibrocartilaginous Dysplasia and Growth Arrest: Case Report.
JBJS Case Connect
October 2024
Department of Pediatric Orthopaedic Surgery, Hospital for Special Surgery, New York, New York.
Case: A pediatric patient with focal fibrocartilaginous dysplasia (FFCD) developed angular deformity and growth arrest despite standard guided growth management. The patient underwent implant-mediated guided growth for proximal tibia varus deformity which recurred; subsequently, a physeal bar of the medial proximal tibia was diagnosed, which progressed to physeal arrest.
Conclusion: Treatment options for FFCD-associated angular deformity include observation and guided growth.
Add-ons in medically assisted reproduction: from evidence to clinical practice.
Hum Reprod
December 2024
Westmead Fertility Centre, Institute of Reproductive Medicine, University of Sydney, Westmead, NSW, Australia.
Morphometric evaluation of the anterior cranial fossa during the prenatal stage in humans and its clinical implications.
PLoS One
December 2024
Specialized Neurological Practice, Neurological Office, Chrząstowice, Poland.
The study examines the morphometric development of the anterior cranial fossa in human fetuses and its clinical implications. The anterior cranial fossa, crucial for protecting the frontal lobes, was analyzed during prenatal development using innovative computer image processing techniques. We hypothesized that the growth of the anterior cranial fossa is not uniform throughout fetal development and that changing geometric relationships are important for possible therapeutic interventions in cases of congenital defects.
View Article and Find Full Text PDF[Audiological aspects of rehabilitation after cochlear implantation in patients with inner ear malformations].
Vestn Otorinolaringol
December 2024
St. Petersburg Research Institute of Ear, Throat, Nose and Speech, St. Petersburg, Russia.
Unlabelled: The article is devoted to the problem of the rehabilitation stage of cochlear implantation in patients with inner ear abnormalities. It provides a detailed analysis of the audiological characteristics of such patients and draws conclusions about approaches to interpreting diagnostic data and speech processors fitting.
Material And Methods: The track records of 80 patients with abnormalities of the inner ear development were retrospectively studied, of which 10 had abnormal structure of the auditory nerve.
Effect of curcumin on methotrexate-induced ovarian damage and follicle reserve in rats: the role of PARP-1 and P53.
Ann Med
December 2025
Department of Histology and Embryology, Bülent Ecevit University, Zonguldak, Turkey.
Background: Methotrexate (MTX) is an agent used in the treatment of many neoplastic and non-neoplastic diseases and is known to cause oxidative damage in normal tissues. Curcumin (Cur) is a natural polyphenol compound with powerful antioxidant and antiapoptotic effects. In this study we investigate the effects of Cur on MTX-induced ovarian damage.
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