AI Article Synopsis
- Inflammatory bowel disease (IBD) is a chronic disorder with unknown causes, and current RNA-sequencing studies face challenges due to experimental variability and differing analysis methods.
- The IBD Transcriptome and Metatranscriptome Meta-Analysis (TaMMA) framework is introduced as a solution to these issues, providing a comprehensive survey of publicly available RNA-sequencing datasets related to IBD.
- TaMMA is an open-source platform that offers an interactive interface, allowing scientists to explore IBD-related transcriptomics and microbial profiles in one place, benefiting the research community focused on IBD.
Article Abstract
Inflammatory bowel disease (IBD) is a class of chronic disorders whose etiogenesis is still unknown. Despite the high number of IBD-related omics studies, the RNA-sequencing data produced results that are hard to compare because of the experimental variability and different data analysis approaches. We here introduce the IBD Transcriptome and Metatranscriptome Meta-Analysis (TaMMA) framework, a comprehensive survey of publicly available IBD RNA-sequencing datasets. IBD TaMMA is an open-source platform where scientists can explore simultaneously the freely available IBD-associated transcriptomics and microbial profiles thanks to its interactive interface, resulting in a useful tool to the IBD community.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10766544 | PMC |
| http://dx.doi.org/10.1038/s43588-021-00114-y | DOI Listing |
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