AI Article Synopsis

  • This case study examines foodborne botulism, highlighting its severe effects like bilateral descending paralysis and respiratory failure caused by botulinum neurotoxin.
  • A 50-year-old obese male experienced rapid onset of symptoms after eating contaminated food, requiring mechanical ventilation and resulting in complications such as tracheostomy.
  • The study emphasizes the effectiveness of diaphragmatic ultrasound as a safe, non-invasive diagnostic tool for assessing diaphragm function in botulism cases and advocates for its routine use to improve patient evaluation.

Article Abstract

This case study explores foodborne botulism, a severe illness caused by botulinum neurotoxin-contaminated food. It leads to bilateral descending paralysis, involving the diaphragm. We highlight diaphragmatic ultrasound as a non-invasive diagnostic tool. A 50-year-old obese male developed diplopia and weakness after consuming contaminated food, rapidly progressing to severe symptoms. Mechanical ventilation became necessary due to respiratory failure. Diaphragmatic ultrasound confirmed bilateral diaphragm paralysis despite early antitoxin treatment. The patient experienced complications, requiring tracheostomy and rehabilitation. After five months, he fully recovered diaphragmatic function. This study underscores botulism's life-threatening nature and the vital role of supportive care. Diaphragmatic ultrasound is a safe and effective method for assessing diaphragmatic function in such cases, obviating ionizing radiation exposure. We recommend its routine use for evaluating botulism-induced paralysis.

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Source
http://dx.doi.org/10.1016/j.toxicon.2024.107609DOI Listing

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