Global infrastructure robustness and local transport efficiency are critical requirements for transportation networks. However, since passengers often travel greedily to maximize their own benefit and trigger traffic jams, overall transportation performance can be heavily disrupted. We develop adaptation rules that leverage optimal transport theory to effectively route passengers along their shortest paths while also strategically tuning edge weights to optimize traffic. As a result, we enforce both global and local optimality of transport. We prove the efficacy of our approach on synthetic networks and on real data. Our findings on the international European highways suggest that thoughtfully devised routing schemes might help to lower car-produced carbon emissions.
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http://dx.doi.org/10.1103/PhysRevLett.131.267401 | DOI Listing |
Nanomicro Lett
January 2025
Energy and Environmental Division, Korea Institute of Ceramic Engineering and Technology, Jinju, Gyeongnam, 52851, Republic of Korea.
All-solid-state batteries (ASSBs) are pursued due to their potential for better safety and high energy density. However, the energy density of the cathode for ASSBs does not seem to be satisfactory due to the low utilization of active materials (AMs) at high loading. With small amount of solid electrolyte (SE) powder in the cathode, poor electrochemical performance is often observed due to contact loss and non-homogeneous distribution of AMs and SEs, leading to high tortuosity and limitation of lithium and electron transport pathways.
View Article and Find Full Text PDFJ Bacteriol
January 2025
Department of Plant & Microbial Biology, University of California Berkeley, Berkeley, California, USA.
Bacteria encounter chemically similar nutrients in their environment, which impact their growth in distinct ways. Among such nutrients are cobamides, the structurally diverse family of cofactors related to vitamin B (cobalamin), which function as cofactors for diverse metabolic processes. Given that different environments contain varying abundances of different cobamides, bacteria are likely to encounter cobamides that enable them to grow robustly and also those that do not function efficiently for their metabolism.
View Article and Find Full Text PDFIET Syst Biol
January 2025
School of Computer Science and Technology, Baotou Medical College, Baotou, China.
Metal ions are significant ligands that bind to proteins and play crucial roles in cell metabolism, material transport, and signal transduction. Predicting the protein-metal ion ligand binding residues (PMILBRs) accurately is a challenging task in theoretical calculations. In this study, the authors employed fused amino acids and their derived information as feature parameters to predict PMILBRs using three classical machine learning algorithms, yielding favourable prediction results.
View Article and Find Full Text PDFInquiry
January 2025
The People's Hospital of Jianyang City, Jianyang, Sichuan Province, China.
This paper aims to establish an intelligent delivery system integrated with track logistics and explores its impact on the clinical transportation of goods. The study analyzed hospital delivery items before and after the implementation of an intelligent delivery system combined with automated track logistics in 2023. Delivery conditions prior to the system's activation served as the control group, while those post-implementation formed the observation group.
View Article and Find Full Text PDFFront Immunol
January 2025
Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Cancer is one of the leading causes of mortality around the world and most of our conventional treatments are not efficient enough to combat this deadly disease. Harnessing the power of the immune system to target cancer cells is one of the most appealing methods for cancer therapy. Nucleotide-based cancer vaccines, especially deoxyribonucleic acid (DNA) cancer vaccines are viable novel cancer treatments that have recently garnered significant attention.
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