AI Article Synopsis
- A study involving 60 children with gastroenteritis was conducted to compare the effectiveness of domperidone suppositories (30 mg) to metoclopramide (10 mg) and a placebo in treating vomiting.
- The results showed that domperidone was significantly more effective in reducing vomiting severity and other related symptoms without any reported side effects during the 24-hour observation period.
- These findings suggest that domperidone suppositories could be the preferred treatment option for pediatric cases of vomiting linked to gastroenteritis.
Article Abstract
In a double-blind trial in 60 children suffering from gastroenteritis complicated by vomiting, it was found that suppositories of domperidone (30 mg) were more effective than either metoclopramide (10 mg) or placebo in reducing the severity of vomiting, nausea and other symptomatic parameters. No side effects were reported throughout the 24 hour period of the trial and the results suggest that domperidone suppositories may well prove to be the drug of choice in such cases of paediatric vomiting.
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