Acute liver failure continues to carry high morbidity and mortality with limited therapeutic options. In this issue of Cell Host & Microbe, Li et al. demonstrate that oral magnesium can protect against acetaminophen-induced liver injury through alterations in the microbiome.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.chom.2023.12.007 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effects of on alcohol-induced liver injury through storing Nrf2/HO-1 pathway and gut microbiota.
Front Pharmacol
November 2024
Shenyang Key Laboratory for Causes and Drug Discovery of Chronic Diesases, Liaoning University, Shenyang, China.
Background: L. Sch. Bip.
View Article and Find Full Text PDFFlavonoids and Their Role in Preventing the Development and Progression of MAFLD by Modifying the Microbiota.
Int J Mol Sci
October 2024
Institute of Medicine, Medical College of Rzeszow University, 35-959 Rzeszow, Poland.
With the increasing prevalence and serious health consequences of metabolic-associated fatty liver disease (MAFLD), early diagnosis and intervention are key to effective treatment. Recent studies highlight the important role of dietary factors, including the use of flavonoids, in improving liver health. These compounds possess anti-inflammatory, antioxidant, and liver-protective properties.
View Article and Find Full Text PDFProtective effect of Zhizi Huangqi Shanzha formula on aflatoxin poisoning in mice and its effect on intestinal flora.
J Tradit Chin Med
October 2024
College of Biotechnology and Pharmaceutical Engineering, West Anhui University, Lu'an 237012, China.
Article Synopsis
- - The study investigates the effects of Zhizi Huangqi Shanzha formula (ZHSF) on liver damage caused by aflatoxin, using methods like blood analysis, liver function tests, and gut microbiota analysis.
- - Results show that ZHSF improves immune response and liver health in poisoned mice by increasing certain blood cell types, reducing liver damage markers, and restoring normal liver tissue and gut bacteria diversity.
- - The findings suggest that ZHSF could be a potential treatment to prevent liver injury from aflatoxin by balancing gut microbiota and counteracting oxidative stress.
Total flavonoids of litchi Seed alleviates schistosomiasis liver fibrosis in mice by suppressing hepatic stellate cells activation and modulating the gut microbiomes.
Biomed Pharmacother
September 2024
Key Laboratory of Longevity and Aging-Related Diseases of Chinese Ministry of Education, Guangxi Medical University, Nanning, Guangxi, China; Key Laboratory of Basic Research on Regional Diseases (Guangxi Medical University), Education Department of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China; Department of Parasitology, Guangxi Medical University, Nanning, Guangxi, China. Electronic address:
Infection with Schistosoma japonicum (S. japonicum) is an important zoonotic parasitic disease that causes liver fibrosis in both human and domestic animals. The activation of hepatic stellate cells (HSCs) is a crucial phase in the development of liver fibrosis, and inhibiting their activation can alleviate this progression.
View Article and Find Full Text PDFComprehensive insights into berberine's hypoglycemic mechanisms: A focus on ileocecal microbiome in db/db mice.
Heliyon
July 2024
Zhejiang Academy of Traditional Chinese Medicine, Hangzhou, China.
The efficacy of berberine in managing diabetes through modulation of gut microbiome has been established through fecal sample analyses. However, relying solely on fecal materials constrains our comprehension of berberine's effects on diverse gastrointestinal locations. This study specifically explores the ileocecal region, a segment characterized by higher microbial diversity than fecal samples.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!