Objective: Obstetric anal sphincter injuries are feared perineal injuries that are associated with increased pelvic floor disorders. The knowledge of influencing factors as the mode of delivery is therefore important. The aim of this study is to compare the rate of obstetric anal sphincter injuries in primiparae after water and bed deliveries.
Study Design: In this retrospective cohort study 3907 primiparae gave birth in water or on a bed in a Swiss teaching hospital. The diagnosis of obstetric anal sphincter injuries was confirmed by a consultant of obstetrics and gynecology and treated by them. The rates of these injuries after water and bed births were compared. Subgroup analysis was performed to detect possible associative factors, such as birth weight, episiotomy, use of oxytocin in first and second stage of labor.
Results: 1844 (47.2 %) of the primiparae had a water delivery and 2063 (52.8 %) a bed delivery. 193 (4.94 %) were diagnosed with obstetric anal sphincter injuries, of which 68 (3.7 %) had a water delivery and 125 (6.1 %) a bed delivery, p < 0.001. Subgroup analysis revealed that, in the first and second stage of labor, the rate of obstetric anal sphincter injuries with oxytocin was significantly lower in water than in bed deliveries; p = 0.025, p < 0.017, respectively. The rate of obstetric anal sphincter injuries in the birth weight or episiotomy subgroups did not reach significance.
Conclusions: In a teaching hospital setting with standardized labor management, primiparae with a water delivery have the lowest risk for obstetric anal sphincter injuries.
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http://dx.doi.org/10.1016/j.ejogrb.2023.12.024 | DOI Listing |
Am J Gastroenterol
November 2024
Division of Neurogastroenterology/Motility, Medical College of Georgia, Augusta University, Augusta, Georgia.
Anorectal neuropathy causes anorectal dysfunction, yet it is poorly recognized. This stems from both a lack of understanding of the extrinsic and intrinsic innervation of the anorectum and tools for evaluation of neuronal function. Our objective was to provide an improved understanding of the neuronal networks of the anorectum and discuss its functional significance.
View Article and Find Full Text PDFAm J Physiol Gastrointest Liver Physiol
January 2025
Wake Forest Institute for Regenerative Medicine, Wake Forest Baptist Medical Center, Winston-Salem, North Carolina, USA.
This study aimed to determine if local injection of CXCL12 reduces sphincter fibrosis, restores sphincter muscle content, vascularization, and innervation, and recruits progenitor cells in a rabbit model of anal sphincter injury and incontinence. Adult female rabbits were assigned to 3 groups: uninjured/no treatment (control), injured/treated (treated), and injured/no treatment (untreated) (n=4 each). Injured groups were anesthetized and a section of external anal sphincter was removed at the 9:00 o'clock position.
View Article and Find Full Text PDFUrogynecology (Phila)
December 2024
University of Pittsburgh, Pittsburgh, PA.
Importance: Wound complications after obstetric anal sphincter injury (OASI) can amplify morbidity and affect quality of life.
Objective: The objective of this study was to evaluate for characteristics associated with wound complications after OASI.
Study Design: This was a retrospective cohort study of patients with an OASI who were evaluated in a postpartum pelvic floor healing clinic between November 1, 2020, and May 16, 2023.
Anal Biochem
December 2024
Internal medicine, Shijiazhuang Fourth Hospital (Obstetrics and Gynecology Hospital Affiliated to Hebei Medical University), Shijiazhuang City, Hebei Province, 050033, China. Electronic address:
Simple yet specific miRNA detection remains an enormous challenge due to its low abundance in samples and the high similarity among homologous miRNAs. Here, we propose a novel fluorescent approach for miRNA detection with greatly elevated accuracy by utilizing exonuclease-iii (Exo-iii) assisted twice target recognition. The proposed method involves a "Sensing probe" engineered with two loop sections to facilitate dual target miRNA recognition.
View Article and Find Full Text PDFEur J Obstet Gynecol Reprod Biol
December 2024
Department of Breast Surgery, General Surgery, Xiangya Hospital, Central South University, Changsha, China. Electronic address:
Background: There was limited evidence on the comparative value of various examination methods for women with obstetric anal sphincter injuries (OASIS).
Objectives: To evaluate diagnostic performance of different examination methods for detecting OASIS.
Methods: We searched PubMed, EMBASE, Cochrane Library, and Web of Science to identify relevant studies from inception to December 2023.
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