Acquiring information that aids decision-making is subject to a trade-off of accuracy versus cost, given that time, effort, or money are required to obtain decision-relevant information. Three studies (N = 2010) investigated the motivational dynamics shaping the priorities that govern this trade-off. Motivational orientations related to both the decision-making process and its outcome were examined. Regulatory focus theory describes two broad orientations to goal pursuit: promotion focus, prioritizing eager achievement, versus prevention focus, prioritizing vigilant security. We hypothesized that when the framing of a decision-making task activates a prevention focus rather than a promotion focus, individuals would be more willing to assume the costs of acquiring additional information before making their decisions. To test this hypothesis, participants made incentivized decisions with the option of acquiring additional information before making a final decision; importantly, obtaining this information incurred financial costs. Results consistently confirmed that prevention-focused decision makers were indeed more willing to assume the costs of acquiring additional information than promotion-focused individuals. The first two studies involved a scenario where participants were indifferent to the specific outcome of the decision process; accuracy was their only concern. In the final study, searchable, accuracy-enhancing information was also related to decision makers' partisan political preferences. Regulatory focus and the preference for partisan-congenial information were observed to be co-occurring but functionally orthogonal drivers of costly information search. Thus, prevention-framed messages can motivate the search for decision-relevant information, even when this search is costly and could lead to disagreeable data.
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http://dx.doi.org/10.1016/j.cognition.2024.105715 | DOI Listing |
Neurogastroenterol Motil
January 2025
Department of Neurology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Background: Constipation is one of the most common non-motor symptoms in patients with Parkinson's disease (PD), which could manifest during the early stage of the disease. However, the etiology of constipation in PD remains largely unknown. Previous studies supported that gastrointestinal dysfunction may be associated with functional connectivity alterations in paraventricular hypothalamic nucleus (PVN).
View Article and Find Full Text PDFBMC Ophthalmol
January 2025
Eye Institute, Affiliated Hospital of Nantong University, Nantong, Jiangsu Province, China.
Background: Human anterior lens capsules (ALCs) have great potential in the treatment of multiple eye diseases, including corneal ulcers, glaucoma, age-related macular degeneration and macular holes. ALCs are also regarded as promising scaffolds for various ocular cells. Here, we investigated different decellularization methods for removing lens epithelial cells (LECs) that adhered to ALCs.
View Article and Find Full Text PDFBMC Infect Dis
January 2025
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, USA.
Introduction: The incidence rate of newly diagnosed HIV infection in Indonesia decreased from 21 per 100,000 in 2011 to 10 per 100,000 in 2021. Despite this progress, AIDS-related deaths among people living with HIV (PLWH) increased from 3.4% in 2010 to 4.
View Article and Find Full Text PDFAnal Chim Acta
February 2025
Fundación IMDEA Nanociencia, Madrid, Spain; Division of Hematopoietic Innovative Therapies, Innovative Therapies Unit. Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), 28040, Madrid, Spain; Advanced Therapies Unit, Instituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD, UAM), 28040, Madrid, Spain. Electronic address:
Background: The detection of genetic sequences represents the gold standard procedure for species discrimination, genetic characterisation of tumours, and identification of pathogens. The development of new molecular detection methods, accessible and cost effective, is of great relevance. Biosensors based on plasmonic nanoparticles, such as gold nanoparticles (AuNPs), provide a powerful and versatile platform for highly sensitive, economic, user-friendly and label-free sensing.
View Article and Find Full Text PDFEJNMMI Phys
January 2025
Institute of Radiology, Nuclear Medicine and Molecular Imaging, Heart and Diabetes Center North Rhine-Westphalia, University Hospital (Ruhr University Bochum), Medical Faculty OWL (Bielefeld University), Bad Oeynhausen, Germany.
Background: The topic of the effect of the patient table on attenuation in myocardial perfusion imaging (MPI) SPECT is gaining new relevance due to deep learning methods. Existing studies on this effect are old, rare and only consider phantom measurements, not patient studies. This study investigates the effect of the patient table on attenuation based on the difference between reconstructions of phantom scans and polar maps of patient studies.
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