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Radial sclerosing lesions (RS, also referred to as "radial scars") and complex sclerosing lesions (CSL) are uncommon breast lesions often grouped together as a single entity in practice. RS/CSL have an incidence of <0.1% to 1% at core needle biopsy (CNB).

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Occult Metastatic Papillary Thyroid Cancer in an Adolescent.

AACE Clin Case Rep

November 2023

Division of Pediatric Endocrinology and Diabetes, Hasbro Children's Hospital, Providence, Rhode Island.

Article Synopsis
  • - Occult papillary thyroid carcinoma (PTC) refers to a situation where PTC spreads but the primary tumor in the thyroid isn't detected through ultrasound before surgery, and there isn't much research on this in children.
  • - A case was reported of a 16-year-old girl who had a painless neck mass, which turned out to be a rare type of PTC, even though initial imaging showed no thyroid abnormalities.
  • - The recommended treatment involves a total thyroidectomy, possibly along with neck dissection, followed by therapies like TSH suppression and radioactive iodine to manage the condition effectively.
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Liver Transplantation for Hilar Cholangiocarcinoma.

Surg Clin North Am

February 2024

Department of Surgery, University of Michigan Health, F6686 UH-South, 1500 East Medical Center Drive, Ann Arbor, MI 48109-5296, USA. Electronic address:

Hilar cholangiocarcinoma (hCCA) is an infiltrative disease that often presents with locally advanced and/or metastatic disease, with a minority of patients eligible for surgical resection. Select patients with unresectable hCCA, or patients with hCCA in the setting of primary sclerosing cholangitis, with tumors less than 3 cm and no evidence of extrahepatic disease, can be effectively treated with neoadjuvant chemoradiation followed by liver transplantation. Staging laparotomy documenting lack of occult metastatic disease, including a portal lymphadenectomy documenting no nodal metastases, is essential to achieve optimal outcomes.

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[Clinical features of primary sclerosing cholangitis and inflammatory bowel disease].

Zhonghua Nei Ke Za Zhi

May 2023

Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.

To explore disease characteristics of primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) and compare the differences between PSC with and without IBD. Study design was cross sectional. Forty-two patients with PSC who were admitted from January 2000 to January 2021 were included.

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Introduction: Viral infections, especially with hepatotropic viruses, may trigger autoimmune liver diseases (AILDs) and deteriorate their course. However, association of previous hepatitis B virus (HBV) infection (presence of anti-HBc with or without anti-HBs or HBV DNA in serum) with AILDs is poorly studied so far. The aim of the study was to assess the prevalence of previous hepatitis B virus infection markers and its clinical significance in patients with autoimmune liver diseases.

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