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Clinical predictors of disease severity in oral lichen planus.
Clin Exp Dermatol
January 2025
Institute of Dentistry, School of Medicine, Medical Sciences & Nutrition, University of Aberdeen, Aberdeen, UK.
Background: The limited understanding of factors influencing the disease progression of oral lichen planus (OLP) poses challenges in delivering effective and personalised treatment for this condition, known to increase the risk of oral cancer and adversely impact patient quality of life.
Objective: This study aimed to systematically identify clinical predictors of disease severity in OLP patients.
Methods: This cross-sectional and single-site prospective study was conducted between December 2021 and February 2024 in the Departments of Oral Medicine and Oral & Maxillofacial Surgery, Aberdeen Royal Infirmary.
The impact of interactions between heavy metals and smoking exposures on the formation of oral microbial communities.
Front Microbiol
December 2024
School of Public Health, Lanzhou University, Lanzhou, Gansu, China.
Introduction: The primary objective of our investigation was to assess the repercussions of prolonged exposure to heavy metals and smoking on the microbiome of the oral buccal mucosa. Concurrently, we aimed to elucidate the intricate interplay between external environmental exposures and the composition of the oral microbial ecosystem, thereby discerning its potential implications for human health.
Methods: Our study cohort was stratified into four distinct groups: MS (characterized by concurrent exposure to heavy metals and smoking), M (exposed solely to heavy metals), S (exposed solely to smoking), and C (comprising individuals serving as a control group).
Modeling diabetes progression with risk factors: A case study in China.
Comput Biol Med
December 2024
School of Mathematics and Computing Science, Guilin University of Electronic Technology, Guilin, 541004, China; Center for Applied Mathematics of Guangxi (GUET), Guilin, 541004, China; Guangxi Colleges and Universities Key Laboratory of Data Analysis and Computation, Guilin, 541004, China. Electronic address:
Background: Approximately 537 million adults worldwide have diabetes, more than 90 % of which is type 2 diabetes mellitus (T2DM). China has the largest number of people living with diabetes. Understanding the epidemiological mechanism can guide diabetes surveillance and control.
View Article and Find Full Text PDFInappropriate Birth Weight for Gestational Age Among Newborns Born at Dessie Referral Hospital: A Retrospective Cohort Study.
Int J Pediatr
December 2024
School of Nursing and Midwifery, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Inappropriate birth weight for gestational age (IBWGA) is linked with obstetric complications like birth asphyxia, hypothermia, and postpartum hemorrhage. This study was aimed at determining the prevalence of IBWGA with factors associated with newborns born at Dessie Referral Hospital, northeast of Ethiopia. We used a retrospective cohort study design and systematic random sampling method to select charts of women giving birth at the hospital from January 2013 to December 2017.
View Article and Find Full Text PDFRisk Factors and Outcomes of Acute Pulmonary Embolism in African Patients: A Systematic Review.
Cureus
November 2024
Cardiothoracic Surgery Unit, Department of Surgery, University of Port Harcourt Teaching Hospital, Port Harcourt, NGA.
Pulmonary embolism is a common cause of morbidity and mortality. Numerous risk factors have been identified that predispose patients to this disease. This study aims to identify these risk factors and the possible outcomes (recovery or mortality) after receiving treatment from any hospital.
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