We describe a clinical case series of 3 patients whose electrocardiogram evolved from type A Wellens syndrome to a type B. We emphasize that the diagnosis and treatment for both patterns is the same and that these findings suggest the evolution of the same disease.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10774787PMC
http://dx.doi.org/10.1016/j.jaccas.2023.102094DOI Listing

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  • - A 66-year-old man experienced increasing exertional chest pain, quickly worsening from NYHA class 2 to class 3, prompting medical investigation despite the lack of a clear trigger.
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  • - Advanced imaging techniques, including coronary angiography and cardiac CT, identified a severe myocardial bridge in the LAD artery, highlighting the need to consider congenital anomalies in cardiac diagnosis and the importance of early recognition for effective treatment.
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Traditionally reflecting critical stenosis of the proximal left anterior descending (LAD) artery, Wellens' syndrome (WS) is an electrocardiogram (ECG) pattern of biphasic or deeply inverted T waves in leads V2 and V3. This critical stenosis can progress to an extensive anterior myocardial infarction (MI) if early and appropriate management is not received promptly. The diagnosis of severe stenosis of the LAD coronary artery can be made by using electrocardiographic changes in Wellens' syndrome.

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Background: Wellen's syndrome may indicate severe stenosis or even occlusion of the proximal left anterior descending coronary artery. It may progress to acute myocardial infarction. Early recognition and an early invasive strategy are critical to avoiding impending myocardial injury.

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The hallmark of Wellens' syndrome is a distinct modification in the precordial T wave of the electrocardiogram (ECG), which usually indicates substantial stenosis of the proximal left anterior descending artery (LAD). Patients with Wellens' syndrome commonly do not exhibit any symptoms of chest pain. This current case report describes a male patient in his early 60s who presented with sporadic chest pain who was subsequently diagnosed with Wellens' syndrome-related electrocardiographic abnormalities.

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