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The BALTO Registry: Long-term results of percutaneous BALloon pericardioTomy in oncological patients. | LitMetric

AI Article Synopsis

  • The study evaluates the safety and effectiveness of percutaneous balloon pericardiotomy (PBP) for treating malignant pericardial effusion (MPE) in cancer patients.
  • Conducted through the BALTO Registry, data from 76 PBP procedures on 61 patients were analyzed, revealing a complication rate of only 2 serious incidents and a high survival discharge rate (95%).
  • The findings suggest PBP is a viable option for MPE, even for patients needing a repeat procedure, with a recurring rate of 24.5% after the first treatment but none after the second.

Article Abstract

Objectives: The aim of this study was to analyze the efficacy and safety of percutaneous balloon pericardiotomy (PBP) in oncological patients who present with a malignant pericardial effusion (MPE).

Background: The use of PBP as a treatment for MPE is not standardized due to the limited evidence. Furthermore, the performance of a second PBP for a recurrence after a first procedure is controversial.

Methods: The BALTO Registry (BALloon pericardioTomy in Oncological patients) is a prospective, single-center, observational registry that includes consecutive PBP performed for MPE from October 2007 to February 2022. Clinical and procedural, characteristics, as well as clinical outcome were analyzed.

Results: Seventy-six PBP were performed in 61 patients (65% female). Mean age was of 66.4 ± 11.2 years. In 15 cases, a second PBP procedure was performed due to recurrence despite the first PBP. The procedure could be performed effectively in all cases with only two serious complications. Ninety-five percent of cases were discharged alive from the hospital. During a median follow-up of 6.3 months (interquartile range [IQR], 0.9-10.8), MPE recurred in 24.5% cases although no recurrences were reported after the second procedure. No evidence of malignant pleural effusion developed on follow-up. The median overall survival time was 5.8 months (IQR, 0.8-10.2) and the time to recurrence after the first PBP was 2.4 months (IQR, 0.7-4.5).

Conclusions: PBP is a safe and effective treatment for MPE. It could be considered an acceptable therapy in most MPE, even in those who recur after a first procedure.

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Source
http://dx.doi.org/10.1002/ccd.30953DOI Listing

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