Hemorrhage control is a crucial aspect of dental procedures, and achieving efficient hemostasis remains a key challenge. The advent of hemostatic dressings has revolutionized the field of dentistry by providing effective and convenient solutions for managing bleeding in vari-ous dental scenarios. This article aims to provide an overview of hemostatic dressings, their mechanisms of action, and their diverse applications in dentistry. We applied the following Pop-ulation, Exposure, Comparator, and Outcomes (PICO) model to assess the document eligibility. A literature search was performed on major search engines, using keywords. At the end of the search, 3 articles were selected that matched the PICO. Three items were selected after the screen-ing process, and bleeding times were analyzed between the control group and the study group. The overall effect showed a substantial and statistically significant difference with bleeding time in favour of HDD-treated patients, showing that this garrison is very useful in controlling bleed-ing for patients taking anticoagulants and antiplatelets (Mean difference - 5.61; C.I. -5.70, - 5.52); Overall, hemostatic dressings have revolutionized the management of bleeding in dentistry, offering a promising solution to achieve optimal hemostasis, improve treatment outcomes, and enhance patient care, particularly Hemcon.
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http://dx.doi.org/10.1186/s12903-023-03568-w | DOI Listing |
Nanomaterials (Basel)
December 2024
Collaborative Innovation Center for Nanomaterials & Devices, College of Physics, Qingdao University, Qingdao 266071, China.
Irregularly shaped wounds cause severe chronic infections, which have attracted worldwide attention due to their high prevalence and poor treatment outcomes. In this study, we designed a new composite functional dressing consisting of traditional Chinese herb carbonized plant powder (CPP) and a polyacrylic acid (PAA)/polyethylenimine (PEI) gel. The rapid gelation of the dressing within 6-8 s allowed the gel to be firmly attached to an irregularly shaped wound surface and avoided powder detachment.
View Article and Find Full Text PDFJ Control Release
December 2024
Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, Zhejiang 325011, China; Department of Periodontics, School & Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China. Electronic address:
Diabetic wound infections are a frequent complication for diabetic patients, and conventional treatment for combating diabetic wound infections relies on antibiotics. However, the misuse and overuse of antibiotics have led to the emergence of drug-resistant bacteria, making these infections challenging to treat. Thus, there is an urgent need for alternative strategies to effectively manage diabetic wound infections.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
School of Pharmacy, Qingdao University, Qingdao 266071, China. Electronic address:
Recent progress in wound healing has highlighted the need for more effective treatment strategies capable of addressing the complex biological and physiological challenges of wound repair. Traditional wound dressings often fail to address the complex and evolving needs of chronic, acute, and burn wounds, particularly in terms of promoting healing, preventing infection, and supporting tissue regeneration. In response to these challenges, calcium alginate fibers (CAFs) have emerged as promising materials, characterized by their exceptional structural properties and diverse biological functions, offering significant commercial potential for the development of advanced wound dressings and therapeutic solutions.
View Article and Find Full Text PDFBiomater Adv
December 2024
National and Local Joint Engineering Laboratory for Synthetic Technology of High Performance Polymer, College of Chemistry, Jilin University, Changchun 130012, China. Electronic address:
On account of the existence of antibiotic resistance, the wound healing of pathogenic infection is still a challenge in modern society. A desirable wound dressing should own the abilities of adhesiveness, hemostasis and good mechanical property, meanwhile the property of eliminating bacteria without side effects is also highly needed. In this work, we established a kind of hydrogel based on carboxymethyl cellulose-graft-tyramine (CMC-Ty) and MXene (TiCT) through employing HO/HRP (horseradish peroxidase) as the initiator, then the as-prepared hydrogel (named CMC-Ty/MXene) was immersed in tannic acid (TA) solution, and this TA-treated hydrogel was called CMC-Ty/MXene+TA.
View Article and Find Full Text PDFBiomater Sci
December 2024
Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China.
Wound healing is a dynamic and complex process involving hemostasis, inflammation, fibroblast proliferation, and tissue remodeling. This process is highly susceptible to bacterial infection, which often leads to impaired and delayed wound repair. While antibiotic therapy remains the primary clinical approach for treating bacteria-infected wounds, its widespread use poses a significant risk of developing bacterial resistance.
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