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| http://dx.doi.org/10.1093/plphys/kiae004 | DOI Listing |
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A One-Stone-Two-Birds Strategy for Photothermal Shape Memory Polyurethane Utilizing Lignin as Monomer and Internal Photothermal Agent.
Macromol Rapid Commun
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Guangdong Provincial Laboratory of Chemistry and Fine Chemical Engineering Jieyang Center, Jieyang, 515200, P. R. China.
Photothermal-triggering shape memory polyurethane allows for precise and controllable shape transformation under remote light stimulation, making it highly desirable for applications in intelligent devices. This study develops a sustainable and high-performance lignin-based polyurethane (LPU) using a one-stone-two-birds strategy, wherein lignin serves as both a synthetic monomer and an internal photothermal agent. The incorporation of lignin significantly improved the mechanical properties of LPU, achieving a tensile strength of 42.
View Article and Find Full Text PDFA One-Stone-Two-Birds Strategy for Intervertebral Disc Repair: Constructing a Reductive Chelation Hydrogel to Mitigate Oxidative Stress and Promote Disc Matrix Reconstruction.
Adv Mater
December 2024
Key laboratory of Biorheological Science and Technology, Ministry of Educations, College of Bioengineering, Chongqing University, Chongqing, 400044, China.
Intervertebral disc degeneration (IVDD) is characterized by fibrosis of nucleus pulposus (NP) cells and accelerated surrounding extracellular matrix catabolism. Bioactive hydrogels have shown significant potential in regulating cellular functions and tissue homeostasis. In this work, a dynamic hydrogel (HA-NCSN/Cu) is designed via the reductive chelation of hyaluronic acid grafted with thiourea (HA-NCSN) and Cu.
View Article and Find Full Text PDFKilling several birds with one stone: A multi-indication population pharmacokinetic model and Bayesian estimator for enteric-coated mycophenolate sodium.
Br J Clin Pharmacol
December 2024
Department of Pharmacology, Toxicology and Pharmacovigilance, CHU de Limoges, Limoges, France.
Aims: Mycophenolic acid (MPA), the active component of enteric-coated mycophenolate sodium (EC-MPS), exhibits highly variable pharmacokinetics. Only a few population pharmacokinetic (popPK) models and Bayesian estimators (MAP-BE) exist for estimating MPA AUC and all in renal transplantation. This study aimed to develop a popPK model and MAP-BE for MPA AUC estimation using a limited sampling strategy (LSS) in solid organ transplant (SOT), haematopoietic stem cell (HSC) recipients and patients with autoimmune diseases (AID) on EC-MPS.
View Article and Find Full Text PDFCorrigendum to 'Multifunctional composite soluble microneedle patch based on "one stone, three birds" strategy for promoting the healing of infectious wounds' [Colloids Surf. B: Biointerfaces, vol. 241 (2024) 114049].
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Skin-Friendly Large Matrix Iontronic Sensing Meta-Fabric for Spasticity Visualization and Rehabilitation Training via Piezo-Ionic Dynamics.
Nanomicro Lett
December 2024
Research Center for Intelligent and Wearable Technology, College of Textiles and Clothing, State Key Laboratory of Bio-Fibers and Eco-Textiles, Health&Protective Smart Textile Research Center of Qingdao, Qingdao University, Qingdao, 266071, People's Republic of China.
Rehabilitation training is believed to be an effectual strategy that can reduce the risk of dysfunction caused by spasticity. However, achieving visualization rehabilitation training for patients remains clinically challenging. Herein, we propose visual rehabilitation training system including iontronic meta-fabrics with skin-friendly and large matrix features, as well as high-resolution image modules for distribution of human muscle tension.
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