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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10735210PMC
http://dx.doi.org/10.36660/abc.20230162DOI Listing

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Stochastic and alternating pacing paradigms to assess the stability of cardiac conduction.

J Mol Cell Cardiol

December 2024

Department of Physiology, University of Bern, Bühlplatz 5, CH-3012 Bern, Switzerland. Electronic address:

Reentry, the most common cause of severe arrhythmias, is initiated by slow conduction and conduction block. Hence, evaluating conduction velocity and conduction block is of primary importance. However, the assessment of cardiac conduction safety in experimental and clinical settings remains elusive.

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Spatially discordant alternans due to periodic pacing site alternation.

Heart Rhythm

July 2024

Department of Pharmacology, University of California, Davis, California. Electronic address:

Background: Bidirectional ventricular tachycardia (BVT) is a rare type of ventricular tachycardia that is characterized by a beat-to-beat alternation in the QRS axis. Previous studies have shown that it is caused by alternating focal activities from 2 locations.

Objective: This study proposes a novel mechanism for the formation of spatially discordant alternans (SDA) due to the periodic pacing site alternation that occurs in BVT.

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