AI Article Synopsis

  • Twin reversed arterial perfusion (TRAP) sequence is a rare complication in identical twin pregnancies sharing a placenta, characterized by one normal "pump" fetus and one abnormal, typically nonviable, "acardiac" fetus.
  • The acardiac fetus relies on the pump fetus for blood supply, which can lead to heart failure and anomalies in the pump fetus, resulting in high mortality rates.
  • Early detection using ultrasound techniques is crucial for managing TRAP, as interrupting the blood flow to the acardiac twin can help reduce the strain on the pump fetus and improve its chances of survival.

Article Abstract

Twin reversed arterial perfusion (TRAP) sequence is a rare pregnancy complication occurs in an identical twin pregnancy that share a single placenta. TRAP sequence is a twin's pregnancy includes a normal-developed viable pump fetus and an abnormal usually nonviable acardiac fetus. The nonviable acardiac fetus depends on the pump fetus for his blood supply and put the pump fetus at risk of high cardiac output heart failure and congenital anomalies with high mortality rate. Gray-scale ultrasound and color and pulsed Doppler imaging is a noninvasive accessible imaging modality for the diagnosis of TRAP sequence. Early diagnosis of such conditions is mandatory in order to apply the proper therapeutic measures and to help the normal developed pump fetus to survive. The main goal of management is to interrupt blood supply to the nonviable acardiac fetus to reduce the strain on the heart of the pump fetus thus, increase the chance of survival.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10772415PMC
http://dx.doi.org/10.12669/pjms.40.1.8088DOI Listing

Publication Analysis

Top Keywords

pump fetus
20
trap sequence
12
nonviable acardiac
12
acardiac fetus
12
twin reversed
8
reversed arterial
8
arterial perfusion
8
fetus
8
blood supply
8
pump
5

Similar Publications

Prenatal and Early Childhood Exposure to Proton Pump Inhibitors and Antibiotics and the Risk of Childhood Cancer: A Nationwide Population-Based Cohort Study.

Drug Saf

December 2024

Department of Microbiology, Tumour and Cell Biology (MTC), Centre for Translational Microbiome Research, Karolinska Institutet, Tomtebodavägen 16, Solna, 171 65, Stockholm, Sweden.

Background: Our microbiome is established during infancy, a time important for later health and long-term effects. Proton pump inhibitors and antibiotics are regularly prescribed during pregnancy. Both drugs cause microbiome disturbance and have been associated with increased cancer risk in adults, but effects of these drugs on the growing foetus and infant remain understudied.

View Article and Find Full Text PDF
Article Synopsis
  • - The TRAP (Twin Reversed Arterial Perfusion) sequence occurs in monochorionic pregnancies where one fetus is healthy and the other is non-viable, leading to risks like high-output cardiac failure in the viable twin.
  • - A 32-year-old woman with TRAP syndrome experienced contractions and spotting at 26 weeks and underwent a cesarean section after concerns of placental abruption; her viable twin was born but later died due to prematurity complications.
  • - This case emphasizes the need for early detection and ongoing prenatal care in managing TRAP syndrome, while also calling for more research into interventions that improve outcomes for affected pregnancies.
View Article and Find Full Text PDF
Article Synopsis
  • Preeclampsia is a pregnancy complication characterized by high blood pressure and vascular issues, influenced by the activity of oxidized low-density lipoprotein (oxLDL) and the LOX-1 receptor.
  • A study used a model where female rats were given a high cholesterol diet to simulate preeclampsia, and researchers assessed the effectiveness of blocking LOX-1 to prevent changes in artery stiffness and microvascular function.
  • The findings suggested that inhibiting LOX-1 may help maintain elastin levels and mitigate some structural changes in large arteries, but it did not significantly affect changes in smaller cerebral arteries or markers of oxidative stress.
View Article and Find Full Text PDF

Objectives: We evaluated fetal cardiovascular physiology and mode of cardiac failure in premature miniature piglets on a pumped artificial placenta (AP) circuit.

Methods: Fetal pigs were cannulated via the umbilical vessels and transitioned to an AP circuit composed of a centrifugal pump and neonatal oxygenator and maintained in a fluid-filled biobag. Echocardiographic studies were conducted to measure ventricular function, umbilical blood flow, and fluid status.

View Article and Find Full Text PDF
Article Synopsis
  • * The fetus showed mild right ventricular (RV) dysplasia, with a notable decrease in TR jet velocity during pregnancy, leading to a postnatal diagnosis of PA/IVS without the expected severe TR.
  • * The conclusion suggests that the presence of mild or no TR in fetal PA/IVS cases can indicate non-biventricular outcomes, even when there are acceptable levels of RV dysplasia.*
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!