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Comparison of Discriminative Ability of Bleeding Risk Criteria and Scores for Predicting Short- and Mid-Term Major Bleeding Events in Patients Undergoing Percutaneous Coronary Intervention. | LitMetric

AI Article Synopsis

  • - The study compared the effectiveness of three different bleeding risk assessment scores (J-HBR, ARC-HBR, and PRECISE-DAPT) in predicting major bleeding events in patients following percutaneous coronary intervention (PCI).
  • - Out of 646 patients, 66.3% were identified as high bleeding risk by the J-HBR score, while the ARC-HBR and PRECISE-DAPT scores identified 49.4% and 43.7%, respectively.
  • - The study found that all three scores had similar predictive abilities for major bleeding events, as indicated by comparable area under the curve (AUC) values across short-term (30 days) and mid-term (2 years) follow-ups.

Article Abstract

This study aimed to compare the discriminative ability of the Japanese Version of High Bleeding Risk (J-HBR), Academic Research Consortium for High Bleeding Risk (ARC-HBR), and Predicting Bleeding Complications in Patients Undergoing Stent Implantation and Subsequent Dual Antiplatelet Therapy (PRECISE-DAPT) scores for predicting major bleeding events. Between January 2017 and December 2020, 646 consecutive patients who underwent successful percutaneous coronary intervention (PCI) were enrolled. We scored the ARC-HBR and J-HBR criteria by assigning 1 point to each major criterion and 0.5 point to each minor criterion. The primary outcome was major bleeding events, defined as Bleeding Academic Research Consortium type 3 or 5 bleeding events. According to the J-HBR, ARC-HBR, and PRECISE-DAPT scores, 428 (66.3%), 319 (49.4%), and 282 (43.7%) patients respectively had a high bleeding risk. During the follow-up period (median, 974 days), 44 patients experienced major bleeding events. The area under the curve (AUC) using the time-dependent receiver operating characteristic curve for major bleeding events was 0.84, 0.82, and 0.83 within 30 days and 0.86, 0.83, and 0.80 within 2 years for the J-HBR, ARC-HBR, and PRECISE-DAPT scores, respectively. The AUC values did not differ significantly among the 3 bleeding risk scores. The J-HBR score had a discriminative ability similar to the ARC-HBR and PRECISE-DAPT scores for predicting short- and mid-term major bleeding events.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10774022PMC
http://dx.doi.org/10.1253/circrep.CR-23-0087DOI Listing

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