Aims: To confirm the improved performance of the micro-hole zone catheter (MHZC) compared to a conventional eyelet catheter (CEC) in male users of clean intermittent catheterizations (CICs).

Methods: Male self-catheterizing subjects, who used hydrophilic sleeved soft/flexible CIC as the only bladder emptying method, were enrolled into a multi-center, randomized, cross-over study performed across six European sites. Subjects tested the MHZC, featuring a drainage zone with 120 micro-holes and a CEC with two eyelets. The study consisted of four study visits (V0-V3), during which endpoints related to catheter performance (urinary flow-stops, bladder emptying, and intra-catheter pressure) were measured and two 4-week test periods at home (T1 and T2) where dipstick hematuria and user perception between catheters were evaluated.

Results: Seventy-three male subjects with non-neurogenic and neurogenic bladder dysfunction (3:2) were enrolled. On average, catheterizations with the MHZC led to close to mean zero flow-stops compared to ≥1 flow-stops with the CEC, during both HCP- and self-led catheterizations (both p < 0.001). Residual urine at first flow-stop was significantly reduced for the MHZC compared to CEC (p = 0.001 and p = 0.004, for HCP- and self-led catheterizations, respectively). This was substantiated by a significantly smaller pressure peak at first flow-stop, a proxy for minimized mucosal suction (both HCP- and self-led catheterizations, p < 0.001). After home-use catheterizations, dipstick hematuria was comparable between catheters, whereas catheterizations were associated with significantly improved perception in favor of MHZC regarding bladder emptying, less blocking sensation, and improved hygienic catheterization compared to the CEC.

Conclusion: This study confirmed the evidence of improved bladder emptying with the MHZC compared to a CEC without the need to reposition the catheter. The MHZC therefore offers an enhanced benefit for the dependent CIC user securing complete bladder emptying in an uninterrupted free flow and reducing the need to reposition the catheter during emptying.

Download full-text PDF

Source
http://dx.doi.org/10.1002/nau.25383DOI Listing

Publication Analysis

Top Keywords

performance micro-hole
8
micro-hole zone
8
zone catheter
8
cross-over study
8
bladder emptying
8
catheter
5
improved emptying
4
emptying performance
4
catheter adult
4
adult male
4

Similar Publications

The triboelectric nanogenerator (TENG) has demonstrated exceptional efficiency in harvesting diverse forms of mechanical energy and converting it into electrical energy. This technology is particularly valuable for powering low-energy electronic devices and self-powered sensors. Most traditional TENGs use single-sided patterned friction pairs, which restrict their effective contact area and overall performance.

View Article and Find Full Text PDF

The fabrication of micro-holes in hard-to-machine materials presents considerable challenges in precision machining. This study proposes a novel approach that employs high-strength micro-grinding tools with a central abrasive grain absence to create micro-holes through helical grinding. Due to the random distribution of abrasive grains, the absence of grains at the tool's center becomes an inevitable technical challenge.

View Article and Find Full Text PDF

The use of array micro-holes is becoming increasingly prevalent across a range of industries, including the aerospace, automotive, electronics, medical and chemical industries. The utilization of advanced sustainable machining technologies offers distinctive advantages and is pivotal for the sustainable manufacture of array micro-holes. This paper examines the sustainable machining techniques commonly employed in the production of array micro-holes, including electrical discharge machining, laser machining, electrochemical machining and composite machining technologies.

View Article and Find Full Text PDF

Technology like micro-hole drilling has progressed because of the machining industry's demand for high-precision micro components. Although micro drilling can be duplicated in theory, many challenges must be overcome before this becomes a reality. Micro-drilling with a thermal-mechanical interaction in the alloy is simulated in Abaqus.

View Article and Find Full Text PDF
Article Synopsis
  • * It analyzes how different laser processing parameters, like energy and scanning overlap, affect the diameter and depth of the micro-holes created in the circuit boards.
  • * Results reveal that the morphology of the drilled holes is influenced by laser energy, with common deposits found during drilling, while the depth of holes increases with higher laser settings without changing their diameter.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!