Pain is a complex process of electrical signal transmission. Electroacupuncture may adjust the bioelectric state of the tissues in painful sites through electrical characteristic structural units (acupoints), thereby exerting analgesic effect. The treatment of diseases with electroacupuncture results from the interaction between the external electric field and the electrical properties of acupoint tissues. Therefore, the state of biological tissues and the parameters of electroacupuncture all affect the therapeutic effect.
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http://dx.doi.org/10.13703/j.0255-2930.20230413-0001 | DOI Listing |
Nutrients
November 2024
Department of Experimental and Clinical Medicine, University of Florence, 50134 Florence, Italy.
Hist Philos Life Sci
November 2024
Amsterdam Neuroscience, Department of Anatomy and Neurosciences, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.
We present a case study of two scientific perspectives on the phenomenon of nerve signal propagation, a bio-electric and a thermodynamic perspective, and compare this case with two accounts of scientific perspectivism: those of Michela Massimi and Juha Saatsi, respectively. We demonstrate that the interaction between the bio-electric perspective and the thermodynamic perspective can be captured in Saatsi's terms of progress in explanatory understanding. Using insights from our case study, we argue that both the epistemic and pragmatic dimensions of scientific understanding are important for increasing explanatory understanding of phenomena.
View Article and Find Full Text PDFACS Omega
November 2024
Unconventional Computing Laboratory, University of the West of England, Coldharbour Ln, Stoke Gifford, Bristol BS16 1QY, U.K.
We propose "kombucha-proteinoid crystal bioelectric circuits" as a sustainable bio-computing platform. These circuits are hybrid biological-inorganic devices that utilize crystal growth dynamics as the physical substrate to convert information. Microfluidic prototypes couple custom-synthesized thermal proteinoids within kombucha cellulose matrices and metastable calcium carbonate solutions.
View Article and Find Full Text PDFSci Rep
November 2024
Dept. Termodinàmica, Facultat de Física, Universitat de València, Burjassot, 46100, Spain.
Cells can compensate a disruptive change in one ion channel by compensatory changes in other channels. We have simulated the adaptation of a multicellular aggregate of non-excitable cells to the electrophysiological perturbation produced by the external blocking of a cation channel. In the biophysical model employed, we consider that this blocking provokes a cell depolarization that opens a voltage-gated calcium channel, thus allowing toxic Ca levels.
View Article and Find Full Text PDFNanomicro Lett
October 2024
Hangzhou Institute of Technology, Xidian University, Hangzhou, 311231, People's Republic of China.
The incidence of large bone defects caused by traumatic injury is increasing worldwide, and the tissue regeneration process requires a long recovery time due to limited self-healing capability. Endogenous bioelectrical phenomena have been well recognized as critical biophysical factors in bone remodeling and regeneration. Inspired by bioelectricity, electrical stimulation has been widely considered an external intervention to induce the osteogenic lineage of cells and enhance the synthesis of the extracellular matrix, thereby accelerating bone regeneration.
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