Background: SARS-CoV-2 vaccination has been reported to improve mental health. However, few relevant data were collected in China. The study aimed to evaluate the impact of SARS-CoV-2 vaccination on the risk of depression in China and risk factors contributing to depression.
Methods: This is a cross-sectional study carried out from May 2020 to July 2021. Participants were widely recruited in China to participate in the survey using an online questionnaire including Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, Athens Insomnia Scale-8.After exclusion of 105 ineligible questionnaires, 9452 participants were included in our final analysis. Chi-square test and Multivariable logistic regression analysis were used to analyze data.
Results: Of the 9452 participants, 7207 were vaccinated. Our results showed that the prevalence of depression decreased significantly after vaccination (56.1 % for unvaccinated participants vs. 19.7 % for vaccinated participants). The prevalence of mild, moderate and severe depression was also significantly lower in the vaccinated participants than in the unvaccinated participants (14.8 % vs 29.0 %, 2.8 % vs 13.3 %, 2.0 % vs 13.8 %, respectively). Besides, among vaccinated participants, male and aged participants had a lower chance of developing depression (AOR = 1.34; AOR = 0.63; AOR = 0.5, respectively). In addition, although with vaccination, participants with anxiety and insomnia were more likely to suffer from depression (AOR = 29.2; AOR = 11.89).
Limitations: The study was a cross-sectional survey. The numbers of participants differed much in the two groups.
Conclusions: The present study confirmed that SARS-CoV-2 vaccination contributed to reducing the prevalence of depression in Chinese adults. Moreover, vaccinated men and older adult participants had less prevalence of depression.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jad.2024.01.035 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Glial activation and nociceptive neuropeptide elevation associated with the development of chronic post-traumatic headache following repetitive blast exposure.
Neurobiol Pain
December 2024
Virginia Polytechnic Institute and State University. Department of Biomedical Engineering, 325 Stranger St., Blacksburg, VA 24060, United States.
Chronic headaches and pain are prevalent in those who are exposure to blast events, yet there is a gap in fundamental data that identifies the pathological mechanism for the chronification of pain. Blast-related post-traumatic headaches (PTH) are understudied and chronic pain behaviors in preclinical models can be vital to help elucidate PTH mechanisms. The descending pain modulatory system controls pain perception and involves specific brain regions such as the cortex, thalamus, pons, and medulla.
View Article and Find Full Text PDFThe prevalence of hypermobile Ehlers-Danlos syndrome at a gender-affirming primary care clinic.
SAGE Open Med
January 2025
Tufts University School of Medicine, Boston, MA, USA.
Objective: This study utilized a sample of trangender, nonbinary, and gender-diverse (TGD) patients to build on emerging literature that suggests that hypermobile Ehlers-Danlos syndrome may be overrepresented in TGD populations. The objective of this retrospective chart review was to determine the prevalence of hypermobile Ehlers-Danlos syndrome syndrome at a gender-affirming primary care clinic.
Methods: A retrospective chart review of medical records was conducted with records between May 2021 and June 2024.
The effectiveness of implemented interventions at the workplace to promote the mental health of working women: A systematic review.
J Educ Health Promot
December 2024
Department of Community Medicine and Family Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Over the last decades, a gradual increase in prevailing mental disorders in the adult population has been observed all over the world. Global estimates of anxiety, stress, depression, and mood disorders prevalence have also been high. Employed women are susceptible to experiencing some symptoms or mental disorders due to their lifestyle or working conditions.
View Article and Find Full Text PDFAcademic stress, perceived parental pressure, and anxiety related to competitive entrance examinations and the general well-being among adolescents - A cross-sectional survey from Karnataka, India.
J Educ Health Promot
December 2024
Department of Child Health Nursing, Manipal College of Nursing, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Background: In this competitive world, students undergo various scholastic stress and mental health issues. The scholastic stress has a great impact on students' life and results in the prevalence of several psychological consequences such as stress-related disorders, anxiety, depression, and nervousness, which disturb their academic performances. Therefore, the present study was conducted to assess academic stress, perceived parental pressure, and anxiety related to competitive entrance examinations and the general well-being among adolescents.
View Article and Find Full Text PDFAdvances in Antidepressant Therapy: Comparing the Efficacy of Selective Serotonin Reuptake Inhibitors (SSRIs), Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs), and Novel Agents.
Cureus
December 2024
Family Medicine, Holy Family Hospital, Rawalpindi, PAK.
Introduction Depression is a prevalent and debilitating condition that often requires long-term medication management. Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) are commonly used but have limitations in efficacy and tolerability for some individuals. New antidepressant drugs targeting multiple pathways have shown potential in recent research.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!